Gondal MN, Butt RN, Shah OS, Sultan MU, Mustafa G, Nasir Z, Hussain R, Khawar H, Qazi
R, Tariq M, Faisal A and Chaudhary SU (2021) A Personalized Therapeutics Approach …

In silico models of biomolecular regulation in cancer, annotated with patient-specific gene
expression data can aid in the development of novel personalized cancer therapeutics …

In silico models of biomolecular regulation in cancer, annotated with patient-specific gene
expression data, can aid in the development of novel personalized cancer therapeutic …

In article number 1900127, Chih-Ming Ho, Dean Ho, Yun Yen and co-workers harness an
artificial intelligence platform that is mechanism free and can dynamically optimize …

Designing multi‐drug regimens often involves target‐and synergy prediction‐based drug
selection, and subsequent dose escalation to achieve the maximum tolerated dose (MTD) of …

A fundamental difficulty in cancer research is the complex, multigenic and genetically
diverse nature of human tumors, recently emphasized by cancer genome sequencing …

Despite development of personalized treatments GI cancer like pancreatic ductal
adenocarcinoma (PDAC) and colorectal cancer (CRC) remain dismal outcomes. While …

One aspect of personalized medicine is aiming at identifying specific targets for therapy
considering the gene expression profile of each patient individually. The real-world …

This thesis uses the valuable tool of mathematical modelling to model and analyse complex
biological systems (Systems Biology) to investigate tumor progression and treatment. It …

Drug discovery and the development of safe and effective therapeutics is an intricate
procedure, further complicated in the context of cancer research by the inherent …