Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population

K Suzuki, M Akiyama, K Ishigaki, M Kanai, J Hosoe… - Nature …, 2019 - nature.com
To understand the genetics of type 2 diabetes in people of Japanese ancestry, we
conducted A meta-analysis of four genome-wide association studies (GWAS; 36,614 cases …

[HTML][HTML] Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

M Imamura, A Takahashi, T Yamauchi, K Hara… - Nature …, 2016 - nature.com
Genome-wide association studies (GWAS) have identified more than 80 susceptibility loci
for type 2 diabetes (T2D), but most of its heritability still remains to be elucidated. In this …

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

YS Cho, CH Chen, C Hu, J Long, RT Hee Ong, X Sim… - Nature …, 2012 - nature.com
We conducted a three-stage genetic study to identify susceptibility loci for type 2 diabetes
(T2D) in east Asian populations. We followed our stage 1 meta-analysis of eight T2D …

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

JS Kooner, D Saleheen, X Sim, J Sehmi, W Zhang… - Nature …, 2011 - nature.com
We carried out a genome-wide association study of type-2 diabetes (T2D) in individuals of
South Asian ancestry. Our discovery set included 5,561 individuals with T2D (cases) and …

Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p …

Y Mori, S Otabe, C Dina, K Yasuda, C Populaire… - Diabetes, 2002 - Am Diabetes Assoc
The genetic background that predisposes the Japanese population to type 2 diabetes is
largely unknown. Therefore, we conducted a 10-cM genome-wide scan for type 2 diabetes …

Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population

F Takeuchi, M Serizawa, K Yamamoto, T Fujisawa… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE To identify novel type 2 diabetes gene variants and confirm previously identified
ones, a three-staged genome-wide association study was performed in the Japanese …

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

JD Cooper, DJ Smyth, AM Smiles, V Plagnol… - Nature …, 2008 - nature.com
We carried out a meta-analysis of data from three genome-wide association (GWA) studies
of type 1 diabetes (T1D), testing 305,090 SNPs in 3,561 T1D cases and 4,646 controls of …

Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening

Y Tabara, H Osawa, R Kawamoto, H Onuma… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE—The present study was conducted to confirm possible associations between
candidate genes from genome-wide association studies and type 2 diabetes in Japanese …

[HTML][HTML] Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia

X Sim, RTH Ong, C Suo, WT Tay, J Liu, DPK Ng… - PLoS …, 2011 - journals.plos.org
Recent large genome-wide association studies (GWAS) have identified multiple loci which
harbor genetic variants associated with type 2 diabetes mellitus (T2D), many of which …

[HTML][HTML] Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies

M Xu, Y Bi, Y Xu, B Yu, Y Huang, L Gu, Y Wu, X Zhu… - PLoS one, 2010 - journals.plos.org
Background Many susceptible loci for type 2 diabetes mellitus (T2DM) have recently been
identified from Caucasians through genome wide association studies (GWAS). We aimed to …