Sepsis associated encephalopathy, occurs in 70% of severe septic cases, following which
survivors exhibit long-term cognitive impairment or global loss of cognitive function …

Sepsis-associated encephalopathy (SAE) is a common complication in critically ill patients
and is associated with a poor prognosis. However, the precise mechanisms underlying …

Background and Aims The systemic host response in sepsis is frequently accompanied by
central nervous system (CNS) dysfunction. Evidence suggests that excessive formation of …

Background Septic encephalopathy is a severe brain dysfunction caused by systemic
inflammation in the absence of direct brain infection. Changes in cerebral blood flow …

Sepsis is a condition that greatly impacts the brain, leading to neurological dysfunction and
heightened mortality rates, making it one of the primary organs affected. Injury to the central …

Background Inflammation increases the risk of developing depression-related symptoms,
and tryptophan metabolism is an important mediator of these behavior changes. Peripheral …

Neurological dysfunction as a result of neuroinflammation has been reported in sepsis and
cause high mortality. High levels of cytokines stimulate the formation of neurotoxic …

Peripheral administration of lipopolysaccharide (LPS) can induce the rodents to a
depression-like state accompanied with remarkable changes of neurotransmitter systems. In …

Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction induced by the
systemic response to infection in septic patients. In the present study, we modeled SAE by …

Sepsis-associated encephalopathy, which presents as delirium and coma, is a significant
complication of sepsis characterized by acute brain dysfunction. The presence of …