Vaccines and monoclonal antibodies: new tools for malaria control

K Miura, Y Flores-Garcia, CA Long… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …

[HTML][HTML] current status of two adjuvanted malaria vaccines and the world health organization (WHO) strategy to eradicate malaria by 2030

DV Parums - … Science Monitor: International Medical Journal of …, 2022 - ncbi.nlm.nih.gov
There is hope that 2023 could bring regulatory approval, licensing, and implementation
programs for safe and effective adjuvanted vaccines to prevent malaria. Clinical trials …

Plasmodium falciparum malaria vaccines in development

J Vekemans, WR Ballou - Expert review of vaccines, 2008 - Taylor & Francis
The development and implementation of a malaria vaccine would constitute a major
breakthrough for global health. Recently, numerous new candidates have entered clinical …

Blood-stage malaria vaccines—recent progress and future challenges

AL Goodman, SJ Draper - Annals of Tropical Medicine & …, 2010 - Taylor & Francis
Plasmodium falciparum malaria is a major global health problem, responsible for up to 1
million deaths each year. Major efforts have been made to develop an effective vaccine …

Malaria vaccines: past, present and future

L Von Seidlein, P Bejon - Archives of disease in childhood, 2013 - adc.bmj.com
The currently available malaria control tools have allowed malaria elimination in many
regions but there remain many regions where malaria control has made little progress. A …

Malaria vaccine R&D in the Decade of Vaccines: breakthroughs, challenges and opportunities

AJ Birkett, VS Moorthy, C Loucq, CE Chitnis… - Vaccine, 2013 - Elsevier
While recent progress has been made in reducing malaria mortality with other interventions,
vaccines are still urgently needed to further reduce the incidence of clinical disease …

A viral-vectored multi-stage malaria vaccine regimen with protective and transmission-blocking efficacies

Y Yusuf, T Yoshii, M Iyori, H Mizukami… - Frontiers in …, 2019 - frontiersin.org
Malaria parasites undergo several stages in their complex lifecycle. To achieve reductions in
both the individual disease burden and malaria transmission within communities, a multi …

The march toward malaria vaccines

SL Hoffman, J Vekemans, TL Richie, PE Duffy - Vaccine, 2015 - Elsevier
In 2013 there were an estimated 584,000 deaths and 198 million clinical illnesses due to
malaria, the majority in sub-Saharan Africa. Vaccines would be the ideal addition to the …

Prospects for Malaria Vaccines: Pre‐Erythrocytic Stages, Blood Stages, and Transmission‐Blocking Stages

J Zheng, H Pan, Y Gu, X Zuo, N Ran… - BioMed research …, 2019 - Wiley Online Library
Malaria is a disease of public health importance in many parts of the world. Currently, there
is no effective way to eradicate malaria, so developing safe, efficient, and cost‐effective …

Novel approaches to identify protective malaria vaccine candidates

WN Chia, YS Goh, L Rénia - Frontiers in microbiology, 2014 - frontiersin.org
Efforts to develop vaccines against malaria have been the focus of substantial research
activities for decades. Several categories of candidate vaccines are currently being …