DNA methylation has recently moved to centre stage in the aetiology of human
neurodevelopmental syndromes such as the fragile X, ICF and Rett syndromes. These …

DNA methylation is a crucial epigenetic modification of the genome that is involved in
regulating many cellular processes. These include embryonic development, transcription …

DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …

DNA methylation is a major determinant in the epigenetic silencing of genes. The
mechanisms underlying the targeting of DNA methylation and the subsequent repression of …

Epigenetic modification of the cytosine base of DNA by its methylation introduced the
possibility that beyond the inherent information contained within the nucleotide sequence …

DNA methylation in mammals is a key epigenetic modification essential to normal genome
regulation and development. DNA methylation patterns are established during early …

DNA methylation is an epigenetic mark that is erased in the early embryo and then re-
established at the time of implantation. In this Review, dynamics of DNA methylation during …

Simple Summary DNA methylation is involved in biological processes including
neurogenesis, aging, and the pathogenesis of brain disorders by the regulation of gene …

DNA methylation is a covalent chromatin modification, characterized by the biochemical
addition of a methyl group (‐CH3) to cytosine nucleotides via a DNA methyltransferase …

The role of DNA methylation in brain development is an intense area of research because
the brain has particularly high levels of CpG and mutations in many of the proteins involved …