Background: Schizophrenia (SCZ) and bipolar disorder (BD) are the result of complex
interactions between genetic vulnerability and environmental factors, including obstetric …

A shared pathway connects schizophrenia and bipolar disorder | Nature Reviews Neuroscience
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The role of stress in precipitating psychotic episodes in schizophrenia and bipolar disorder
has long been acknowledged. However, the neurobiological mechanism/s of this …

Aberrations in neurodevelopmental trajectories have been implicated in the neurobiology of
several mental disorders and evidence indicates a pathophysiological and genetic overlap …

Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric disorders which result
from complex interplay between genetic and environmental factors. It is well-established that …

The debate endures as to whether schizophrenia and bipolar disorder are separate entities
or different manifestations of a single underlying pathological process. Here, we argue that …

Highlights•Genetic analysis of schizophrenia and bipolar disorder is uncovering a wide
array of significant effects.•These results support a model of polygenic inheritance for both …

Schizophrenia (SCZ) and bipolar disorder (BD) are severe psychiatric disorders that share
clinical features and several risk genes. Important information about their genetic …

Kraepelin's observations of the differences in the course and outcome of dementia praecox
and manic depression fundamentally influenced thinking about bipolar disorder (BP) and …

Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with
high heritability rates. The contribution of genetic factors to the etiology of these disorders is …