Investigation of inflammation in Lewy body dementia: a systematic scoping review

PM Loveland, JJ Yu, L Churilov, N Yassi… - International Journal of …, 2023 - mdpi.com
Inflammatory mechanisms are increasingly recognized as important contributors to the
pathogenesis of neurodegenerative diseases, including Lewy body dementia (LBD). Our …

Systemic inflammation in Lewy body diseases: a systematic review

E King, A Thomas - Alzheimer Disease & Associated Disorders, 2017 - journals.lww.com
Few studies have investigated the role of inflammation in Lewy body dementia (LBD) and
variable results have been found. We systematically reviewed the literature for evidence of …

Inflammatory panel cytokines are elevated in the neocortex of late-stage Alzheimer's disease but not Lewy body dementias

YL Chai, JH Lee, JR Chong, C Ballard… - Journal of …, 2023 - Springer
Background Chronically dysregulated neuroinflammation has been implicated in
neurodegenerative dementias, with separate studies reporting increased brain levels of …

[HTML][HTML] Inflammation in dementia with Lewy bodies

J Amin, D Erskine, PC Donaghy… - Neurobiology of …, 2022 - Elsevier
Dementia with Lewy bodies (DLB) is the second most common neurodegenerative cause of
dementia, behind Alzheimer's disease (AD). The profile of inflammation in AD has been …

Peripheral inflammation in prodromal Alzheimer's and Lewy body dementias

E King, JT O'Brien, P Donaghy, C Morris… - Journal of Neurology …, 2018 - jnnp.bmj.com
Objectives There is growing evidence for the role of systemic inflammation in Alzheimer's
disease (AD) and other neurodegenerative diseases; however the systemic inflammatory …

Peripheral inflammation could be a prodromal indicator of dementia

H Wood - Nature Reviews Neurology, 2018 - nature.com
Evidence is accumulating that the pathogenesis of Alzheimer disease (AD) and other
neurodegenerative conditions involves mechanisms that operate outside the brain, and new …

Peripheral immunophenotype in dementia with Lewy bodies and Alzheimer's disease: an observational clinical study

J Amin, D Boche, Z Clough, J Teeling… - Journal of Neurology …, 2020 - jnnp.bmj.com
Background Inflammation plays a key role in the aetiology and progression of Alzheimer's
disease (AD). However, the immunophenotype of the second most common …

Neuroinflammation in Lewy body dementia

A Surendranathan, JB Rowe, JT O'Brien - Parkinsonism & related disorders, 2015 - Elsevier
Neuroinflammation is increasingly recognized as a key factor in the pathogenesis of
neurodegenerative conditions. However, it remains unclear whether it has a protective or …

[HTML][HTML] Correlation of microglial activation with white matter changes in dementia with Lewy bodies

N Nicastro, E Mak, GB Williams, A Surendranathan… - NeuroImage: Clinical, 2020 - Elsevier
Dementia with Lewy bodies (DLB) is characterized by alpha-synuclein protein deposition
with variable degree of concurrent Alzheimer's pathology. Neuroinflammation is also …

Early microglial activation and peripheral inflammation in dementia with Lewy bodies

A Surendranathan, L Su, E Mak, L Passamonti… - Brain, 2018 - academic.oup.com
Inflammation is increasingly recognized as part of the pathology of neurodegenerative
conditions such as Alzheimer's disease and Parkinson's disease, but its role in dementia …