Current perspective on the use of angiotensin-converting enzyme inhibitors in the management of coronary (atherosclerotic) artery disease

JWM Cheng, MN Ngo - Annals of Pharmacotherapy, 1997 - journals.sagepub.com
OBJECTIVE: To review the pathophysiology of atherosclerosis, the role of the renin—
angiotensin system in atherogenesis, and studies supporting the potential beneficial effects …

Potential indications for angiotensin-converting enzyme inhibitors in atherosclerotic vascular disease

A Halkin, G Keren - The American journal of medicine, 2002 - Elsevier
Angiotensin-converting enzyme (ACE) inhibitors are well established as first-line therapy for
patients with left ventricular dysfunction, diabetic patients with hypertension or renal disease …

Anti-ischemic effects of angiotensin-converting enzyme inhibitors: a future therapeutic perspective

E Ambrosioni, S Bacchelli… - Journal of …, 2001 - journals.lww.com
The renin-angiotensin system and angiotensin-converting enzyme (ACE) are increasingly
being implicated in the pathogenesis of coronary artery disease and its sequelae and the …

Potential role of angiotensin converting enzyme inhibitors in the treatment of atherosclerosis

B Pitt - European heart journal, 1995 - academic.oup.com
Recent clinical data from the SOLVD (Studies on Left Ventricular Dysfunction) and SAVE
(Survival and Ventricular Enlargement) studies have shown a significant reduction in …

Angiotensin converting enzyme inhibition and coronary artery disease

CJ Pepine - Journal of Hypertension, 1994 - journals.lww.com
Purpose: To review the evidence on the effects of angiotensin converting enzyme (ACE)
inhibitors in coronary artery disease. Experimental studies: In studies of experimental …

Should an angiotensin-converting enzyme inhibitor be standard therapy for patients with atherosclerotic disease?

JH O'Keefe, M Wetzel, RR Moe, K Brosnahan… - Journal of the American …, 2001 - jacc.org
Angiotensin-converting enzyme (ACE) inhibitors appear to possess unique cardioprotective
benefits, even when used in patients without high blood pressure or left ventricular …

Emerging concepts: angiotensin-converting enzyme inhibition in coronary artery disease

GB John Mancini - Cardiovascular drugs and therapy, 1996 - Springer
Angiotensin-converting enzyme (ACE) inhibitors have played a highly beneficial role in the
therapy of hypertension and congestive heart failure. Detailed analysis of some of the heart …

The effects of ACE inhibition on progression of atherosclerosis

N Sharpe - Journal of cardiovascular pharmacology, 1993 - journals.lww.com
Angiotensin-converting enzyme inhibitors have been extensively studied and established in
the treatment of hypertension, heart failure, and ventricular dysfunction. They have various …

Angiotensin-converting enzyme inhibition to enhance vascular health—clinical and research models

GL Bakris - American journal of hypertension, 2001 - academic.oup.com
Protection of the endothelium, the metabolically active inner lining of the vasculature,
appears to be a key factor in maintaining cardiovascular (CV) health. The endothelium …

Can angiotensin-converting enzyme inhibitors reverse atherosclerosis?

JP Higgins - Southern medical journal, 2003 - go.gale.com
Angiotensin II, a potent vasoconstrictor, is mainly present in the vascular endothelium.
Multiple studies have confirmed that angiotensin-converting enzyme (ACE) inhibitors, which …