Cancer is one of the most frequently diagnosed malignant diseases worldwide, posing a
serious, long-term threat to patients' health and life. Systemic chemotherapy remains the first …

Chemoresistance including intrinsic and acquired anticancer drug resistance continues to
be a primary hindrance towards curative cancer treatment. Therefore, deciphering the …

Non-coding RNAs (ncRNAs) have been implicated in most cellular functions. The disruption
of their function through somatic mutations, genomic imprinting, transcriptional and post …

The acquisition of cancer cell resistance to conventional chemotherapeutics is considered
the major driver of treatment failure and disease recurrence in most solid and hematological …

Chemotherapy is one of the fundamental methods of cancer treatment. However, drug
resistance remains the main cause of clinical treatment failure. We comprehensively review …

Chemotherapy is one of the important and effective options for cancer treatment in the past
decades. Although the response rate of initial chemotherapy is considerably high in certain …

Non-coding RNAs are important regulators of gene expression and transcription. It is well
established that impaired non-coding RNA expression especially the one of long non …

Chemotherapy is one of the basic treatments for cancers; however, drug resistance is mainly
responsible for the failure of clinical treatment. The mechanism of drug resistance is …

Drug resistance is one of the major reasons for the failure of cancer therapies. Although our
understanding of resistance to targeted cancer drugs remains incomplete, new and more …

Chemotherapy has been extensively used in tumor treatment, including either systemic or
local treatment. Miserably, in many kinds of cancers, chemotherapy is gradually insensitive …