The engineering of genetic circuits with predictive functionality in living cells represents a
defining focus of the expanding field of synthetic biology. This focus was elegantly set in …

One defining goal of synthetic biology is the development of engineering-based approaches
that enable the construction of gene-regulatory networks according to 'design specifications' …

Although there has been considerable progress in the development of engineering
principles for synthetic biology, a substantial challenge is the construction of robust circuits …

Synthetically engineered genetic circuits can perform a wide variety of tasks but are
generally less accurate than natural systems. Here we revisit the first synthetic genetic …

Understanding how biochemical networks lead to large-scale nonequilibrium self-
organization and pattern formation in life is a major challenge, with important implications for …

Networks of interacting biomolecules carry out many essential functions in living cells, but
the 'design principles' underlying the functioning of such intracellular networks remain poorly …

We show that phase-repulsive coupling eliminates oscillations in a population of synthetic
genetic clocks. For this, we propose an experimentally feasible synthetic genetic network …

Blinkers on. A synthetic gene circuit that works like a clock turns on fluorescent proteins that
make these E. coli flash on and off. each other because they installed the wiring. But …

Population cycles that persist in time and are synchronized over space pervade ecological
systems, but their underlying causes remain a long-standing enigma,,,,,,,,,,. Here we …

Diverse biochemical rhythms are generated by thousands of cellular oscillators that
somehow manage to operate synchronously. In fields ranging from circadian biology to …