Regdanvimab: first approval

YY Syed - Drugs, 2021 - Springer
Regdanvimab (Regkirona™) is a recombinant human monoclonal antibody targeted against
the severe acute respiratory syndrome coronavirus 2. It is being developed by Celltrion Inc …

[HTML][HTML] Regdanvimab in patients with mild-to-moderate SARS-CoV-2 infection: a propensity score–matched retrospective cohort study

S Lee, SO Lee, JE Lee, KH Kim, SH Lee… - International …, 2022 - Elsevier
Abstract Background Regdanvimab (CT-P59) is a neutralizing antibody authorized in
Republic of Korea for the treatment of adult patients with moderate or mild-COVID-19 who …

Efficacy and safety of regdanvimab (CT-P59): a phase 2/3 randomized, double-blind, placebo-controlled trial in outpatients with mild-to-moderate coronavirus disease …

A Streinu-Cercel, O Săndulescu… - Open forum …, 2022 - academic.oup.com
Abstract Background Regdanvimab (CT-P59) is a monoclonal antibody with neutralizing
activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report …

Effectiveness of regdanvimab treatment in high-risk COVID-19 patients to prevent progression to severe disease

JY Lee, JY Lee, JH Ko, M Hyun, HA Kim… - Frontiers in …, 2021 - frontiersin.org
Objective To evaluate clinical effectiveness of regdanvimab, a monoclonal antibody agent
for treating coronavirus 2019 (COVID-19). Methods A retrospective cohort study was …

Casirivimab/imdevimab: first approval

ED Deeks - Drugs, 2021 - Springer
Abstract Casirivimab/imdevimab (Ronapreve™; REGEN-COV™) is a co-packaged
combination of two neutralizing immunoglobulin gamma 1 (IgG1) human monoclonal …

A randomized clinical trial of regdanvimab in high-risk patients with mild-to-moderate coronavirus disease 2019

JY Kim, O Săndulescu, LL Preotescu… - Open forum …, 2022 - academic.oup.com
Background We evaluated clinical effectiveness of regdanvimab (CT-P59), a severe acute
respiratory syndrome coronavirus 2 neutralizing monoclonal antibody, in reducing disease …

REGEN-COV antibody combination and outcomes in outpatients with Covid-19

DM Weinreich, S Sivapalasingam… - … England Journal of …, 2021 - Mass Medical Soc
Background In the phase 1–2 portion of an adaptive trial, REGEN-COV, a combination of the
monoclonal antibodies casirivimab and imdevimab, reduced the viral load and number of …

[HTML][HTML] An EUA for Bamlanivimab-A monoclonal anti-body for COVID-19

M Orders - Med Lett Drugs Ther, 2020 - secure.medicalletter.org
The investigational neutralizing IgG1 monoclonal antibody bamlanivimab (LY-CoV555; Lilly)
has been granted an FDA Emergency Use Authorization (EUA) for treatment of recently …

REGEN-COV antibody cocktail clinical outcomes study in Covid-19 outpatients

DM Weinreich, S Sivapalasingam, T Norton, S Ali… - MedRxiv, 2021 - medrxiv.org
Background REGEN-COV antibody cocktail (casirivimab with imdevimab) rapidly reduced
viral load and decreased medically-attended visits in the phase 1/2 portion of this trial; …

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, PW Horby… - Medrxiv, 2021 - medrxiv.org
Background REGEN-COV is a combination of 2 monoclonal antibodies (casirivimab and
imdevimab) that bind to two different sites on the receptor binding domain of the SARS-CoV …