This review describes the usefulness of in silico design approaches in the design of new radiopharmaceuticals, especially peptide-based radiotracers (including peptidomimetics) …
M Failla, G Floresta, V Abbate - RSC Medicinal Chemistry, 2023 - pubs.rsc.org
In medical imaging, techniques such as magnetic resonance imaging, contrast-enhanced computerized tomography, and positron emission tomography (PET) are extensively …
Radiolabeled peptides are a valuable class of radiotracer that occupies the space between small molecules and large biologics, and are able to exploit the advantages of both classes …
SM Okarvi, HR Maecke - Peptide applications in biomedicine …, 2018 - Elsevier
Regulatory peptides—naturally occurring peptide molecules, with a size of usually less than 30 amino acids—play vital roles in all living systems and are responsible for many essential …
L Aloj, G Morelli - Current pharmaceutical design, 2004 - ingentaconnect.com
Recent years have seen an increased effort in the development of peptide based radiopharmaceuticals for nuclear medicine applications in imaging and therapy. This field is …
Radiopharmaceuticals play a pivotal role in the rapidly emerging field of personalized medicine. 1 In disease states, altered expression or aggregation of specific molecules allow …
F Maleki, AM Farahani, F Rezazedeh… - Bioorganic chemistry, 2020 - Elsevier
Molecular imaging techniques are increasingly being used in localization, staging and therapy control of cancer. Due to their unique target specificity for the endogenous receptors …
BJ Evans, AT King, A Katsifis, L Matesic, JF Jamie - Molecules, 2020 - mdpi.com
The high affinity and specificity of peptides towards biological targets, in addition to their favorable pharmacological properties, has encouraged the development of many peptide …
YQ Yan, H Wang, Y Zhao - Chinese Chemical Letters, 2022 - Elsevier
Radionuclide imaging is now the premier imaging method in clinical practice for its high sensitivity and tomographic capability. Current clinically available radio imaging methods …