[HTML][HTML] Epigenetic and transcriptional regulation of the human angiotensinogen gene by high salt
S Perla, A Kumar - bioRxiv, 2023 - ncbi.nlm.nih.gov
Hypertension is caused by a combination of genetic and environmental factors.
Angiotensinogen (AGT) is a component of RAAS, that regulates blood pressure. The human …
Angiotensinogen (AGT) is a component of RAAS, that regulates blood pressure. The human …
[图书][B] Epigenetic Regulation of the Human Angiotensinogen Gene by Single Nucleotide Polymorphisms
SK Perla - 2018 - search.proquest.com
Hypertension is a complex disease caused by a combination of genetic and environmental
factors. Renin-angiotensin system (RAS) dysfunction leads to essential hypertension …
factors. Renin-angiotensin system (RAS) dysfunction leads to essential hypertension …
Epigenetic Regulation of the Human Angiotensinogen Gene: Role of Individual SNPs and Implication for Hypertension
B Mopidevi, S Perla, N Puri, A Kumar - Hypertension, 2015 - Am Heart Assoc
Hypertension is a complex disease caused by a combination of genetic and environmental
factors. Renin angiotensin system (RAS) dysfunction is a frequent accompaniment of …
factors. Renin angiotensin system (RAS) dysfunction is a frequent accompaniment of …
[HTML][HTML] Dexamethasone promotes hypertension by allele-specific regulation of the human angiotensinogen gene
VG Pandey, S Jain, A Rana, N Puri, SKC Arudra… - Journal of Biological …, 2015 - ASBMB
The human angiotensinogen (hAGT) gene has polymorphisms in its 2.5-kb promoter that
form two haplotype (Hap) blocks:− 6A/G (− 1670A/G,− 1562C/T, and− 1561T/C) and …
form two haplotype (Hap) blocks:− 6A/G (− 1670A/G,− 1562C/T, and− 1561T/C) and …
[HTML][HTML] The transcriptional regulation of the human angiotensinogen gene after high-fat diet is haplotype-dependent: Novel insights into the gene-regulatory networks …
A Rana, S Jain, N Puri, M Kaw, N Sirianni, D Eren… - PLoS …, 2017 - journals.plos.org
Single nucleotide polymorphisms (SNPs) in the human angiotensinogen (hAGT) gene may
modulate its transcription and affect the regulation of blood pressure via activation of the …
modulate its transcription and affect the regulation of blood pressure via activation of the …
[HTML][HTML] Dynamic regulation of the angiotensinogen gene by DNA methylation, which is influenced by various stimuli experienced in daily life
M Demura, Y Demura, Y Takeda, K Saijoh - Hypertension Research, 2015 - nature.com
Angiotensinogen (AGT) has a central role in maintaining blood pressure and fluid balance.
DNA methylation is an epigenomic modification maintaining a steady pattern in somatic …
DNA methylation is an epigenomic modification maintaining a steady pattern in somatic …
The role of DNA methylation and histone modifications in blood pressure: a systematic review
V Gonzalez-Jaramillo, E Portilla-Fernandez… - Journal of human …, 2019 - nature.com
Epigenetic mechanisms might play a role in the pathophysiology of hypertension, a major
risk factor for cardiovascular disease and renal failure. We aimed to systematically review …
risk factor for cardiovascular disease and renal failure. We aimed to systematically review …
Differential expression and DNA methylation of angiotensin type 1A receptors in vascular tissues during genetic hypertension development
F Pei, X Wang, R Yue, C Chen, J Huang… - Molecular and cellular …, 2015 - Springer
Angiotensin type 1a receptor (AT1aR) is thought to play an important role in the
development of hypertension. However, it is unknown how the AT1aR expression in …
development of hypertension. However, it is unknown how the AT1aR expression in …
[HTML][HTML] Transgenic mice with− 6A haplotype of the human angiotensinogen gene have increased blood pressure compared with− 6G haplotype
S Jain, A Tillinger, B Mopidevi, VG Pandey… - Journal of biological …, 2010 - ASBMB
Hypertension is a serious risk factor for cardiovascular disease, and the angiotensinogen
(AGT) gene locus is associated with human essential hypertension. The human AGT (hAGT) …
(AGT) gene locus is associated with human essential hypertension. The human AGT (hAGT) …
[HTML][HTML] The underlying mechanisms of DNA methylation in high salt memory in hypertensive vascular disease
N Liu, Y Chen, Y Wang, S Wu, J Wang, L Qi, T Deng… - Scientific Reports, 2024 - nature.com
This study demonstrates the effect and DNA methylation-related mechanisms of a high-salt
diet and salt memory-induced hypertension and vasculopathy. Thirty Sprague Dawley rats …
diet and salt memory-induced hypertension and vasculopathy. Thirty Sprague Dawley rats …
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