An overview of the roles of the gut microbiome in obesity and diabetes

GM Barlow, EA Lin, R Mathur - Nutritional and therapeutic interventions for …, 2018 - Elsevier
Obesity and diabetes represent two of the most significant noncommunicable challenges in
healthcare worldwide. The gut microbiome is now known to play key roles in both of these …

Gut microbiota and obesity: lessons from the microbiome

PD Cani - Briefings in functional genomics, 2013 - academic.oup.com
The distal gut harbours microbial communities that outnumber our own eukaryotic cells. The
contribution of the gut microbiota to the development of several diseases (eg obesity, type 2 …

[HTML][HTML] Intestinal microbiota contributes to energy balance, metabolic inflammation, and insulin resistance in obesity

JF Cavallari, JD Schertzer - Journal of Obesity & Metabolic …, 2017 - ncbi.nlm.nih.gov
Obesity is associated with increased risk of developing metabolic diseases such as type 2
diabetes. The origins of obesity are multi-factorial, but ultimately rooted in increased host …

Role of the gut microbiome in obesity and diabetes mellitus

GM Barlow, A Yu, R Mathur - Nutrition in clinical practice, 2015 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) and obesity represent two of the biggest global health
challenges of this century and are associated with significant comorbidities and healthcare …

[HTML][HTML] The human microbiome and obesity: moving beyond associations

P Maruvada, V Leone, LM Kaplan, EB Chang - Cell host & microbe, 2017 - cell.com
Mounting evidence indicates that the gut microbiome responds to diet, antibiotics, and other
external stimuli with speed and high precision and in ways that impact a variety of metabolic …

Gut microbiome and its role in obesity and insulin resistance

CJ Lee, CL Sears, N Maruthur - … of the New York Academy of …, 2020 - Wiley Online Library
Obesity is a complex metabolic disease caused, in part, by the interaction between an
individual's genetics, metabolism, and environment. Emerging evidence supports the role of …

Changes in the Gut Microbiome as Seen in Diabetes and Obesity

GM Barlow, S Celly, R Mathur - Clinical Understanding of the Human Gut …, 2024 - Springer
Diabetes rates have risen to the point where 1 in 10 adults worldwide have diabetes, and
obesity rates have more than tripled since 1975. These conditions are interrelated and …

16 Gut Microbiome and Obesity

PD Cani - Handbook of Obesity, Two-Volume Set, 2019 - books.google.com
The role of gut microbes in human physiology was largely underestimated until the past two
decades. Once characterized as bystanders in the intestinal tract, the gut microbiota is now …

The gut microbiota as a therapeutic target for obesity: a scoping review

S Santos-Paulo, SP Costello, SC Forster… - Nutrition Research …, 2022 - cambridge.org
There is mounting evidence that microbiome composition is intimately and dynamically
connected with host energy balance and metabolism. The gut microbiome is emerging as a …

The therapeutic potential of manipulating gut microbiota in obesity and type 2 diabetes mellitus

RS Kootte, A Vrieze, F Holleman… - Diabetes, Obesity …, 2012 - Wiley Online Library
Obesity and type 2 diabetes mellitus (T2DM) are attributed to a combination of genetic
susceptibility and lifestyle factors. Their increasing prevalence necessitates further studies …