Background In patients with severe heart failure, prolonged unloading of the myocardium
with the use of a left ventricular assist device has been reported to lead to myocardial …

Background Implantable left ventricular assist devices have benefited patients with end-
stage heart failure as a bridge to cardiac transplantation, but their long-term use for the …

Background—We have previously shown that a specific combination of drug therapy and left
ventricular assist device unloading results in significant myocardial recovery, sufficient to …

Background This study assessed the effect of prolonged left ventricular unloading on native
ventricular function. Methods We reviewed data from 31 patients (30 men, 1 woman) …

OBJECTIVE: The REMATCH trial compared the use of left ventricular assist devices with
optimal medical management for patients with end-stage heart failure. When the trial met its …

Background—Mechanical, histological, and biochemical improvement has been described
in patients after left ventricular assist device (LVAD) support. Explantation of the LVADs …

As experience has grown with the use of mechanical circulatory support systems in patients
with cardiogenic shock, many anecdotes have been noted where myocardial recovery …

Heart failure is one of the major causes of morbidity and mortality in both developed and
developing countries [1, 2]. Despite advances in the medical management of heart failure …

Congestive heart failure affects about 1 percent of adults in the United States1 and is a
contributing factor in over 250,000 deaths annually. 2 It is diagnosed in 400,000 Americans …

Left ventricular assist devices are becoming an increasingly prevalent therapy for patients
with Stage D heart failure with reduced ejection fraction. Technological advances have …