Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators

N Yasmeen, H Selvaraj, SS Lakhawat, M Datta… - Biochemical …, 2023 - Elsevier
Abstract Fatal “cytokine storms (CS)” observed in critically ill COVID-19 patients are
consequences of dysregulated host immune system and over-exuberant inflammatory …

Role of specialized pro-resolving lipid mediators and their receptors in virus infection: a promising therapeutic strategy for SARS-CoV-2 cytokine storm

CH Lee - Archives of pharmacal research, 2021 - Springer
Unexpected viral infections outbreaks, significantly affect human health, leading to
increased mortality and life disruption. Among them is the severe acute respiratory …

[HTML][HTML] Specialized pro-resolving lipid mediators regulate inflammatory macrophages: A paradigm shift from antibiotics to immunotherapy for mitigating COVID-19 …

V Kumar, N Yasmeen, AA Chaudhary… - Frontiers in molecular …, 2023 - frontiersin.org
The most severe clinical manifestations of the horrifying COVID-19 disease, that claimed
millions of lives during the pandemic time, were Acute respiratory distress syndrome …

[HTML][HTML] Specialized pro-resolving lipid mediators and resolution of viral diseases

G Ferri, M Mucci, D Mattoscio, A Recchiuti - Prostaglandins & Other Lipid …, 2023 - Elsevier
The COVID-19 pandemics has made sparkly evident the importance of acute inflammation
and its timely resolution to protect humans from pathogenic viruses while sparing them from …

E-series resolvin metabolome, biosynthesis and critical role of stereochemistry of specialized pro-resolving mediators (SPMs) in inflammation-resolution: Preparing …

CN Serhan, S Libreros, R Nshimiyimana - Seminars in immunology, 2022 - Elsevier
The COVID-19 pandemic has raised international awareness of the importance of rigorous
scientific evidence and the havoc caused by uncontrolled excessive inflammation. Here we …

The function of specialized pro-resolving endogenous lipid mediators, vitamins, and other micronutrients in the control of the inflammatory processes: Possible role in …

CG Gallo, S Fiorino, G Posabella, D Antonacci… - Prostaglandins & other …, 2022 - Elsevier
Inflammation is an essential protective response against harmful stimuli, such as invading
pathogens, damaged cells, or irritants. Physiological inflammation eliminates pathogens and …

[HTML][HTML] Resolvins, protectins, and maresins: DHA-derived specialized pro-resolving mediators, biosynthetic pathways, synthetic approaches, and their role in …

I Ferreira, F Falcato, N Bandarra, AP Rauter - Molecules, 2022 - mdpi.com
Marine organisms are an important source of natural products with unique and diverse
chemical structures that may hold the key for the development of novel drugs …

Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?

D Panigrahy, MM Gilligan, S Huang, A Gartung… - Cancer and metastasis …, 2020 - Springer
Abstract Severe coronavirus disease (COVID-19) is characterized by pulmonary hyper-
inflammation and potentially life-threatening “cytokine storms”. Controlling the local and …

The role of innate immunity and bioactive lipid mediators in COVID-19 and influenza

S Sahanic, J Loeffler-Ragg, P Tymoszuk… - Frontiers in …, 2021 - frontiersin.org
In this review, we discuss spatiotemporal kinetics and inflammatory signatures of innate
immune cells specifically found in response to SARS-CoV-2 compared to influenza virus …

[HTML][HTML] Specialized pro-resolving mediators as potential regulators of inflammatory macrophage responses in COVID-19

MG Balta, E Papathanasiou… - Frontiers in …, 2021 - frontiersin.org
The recent outbreak of SARS-CoV2 has emerged as one of the biggest pandemics of our
century, with outrageous health, social and economic consequences globally. Macrophages …