Effect of intermediate-dose vs standard-dose prophylactic anticoagulation on thrombotic events, extracorporeal membrane oxygenation treatment, or mortality among …

S Mazloomzadeh, S Khaleghparast, B Ghadrdoost… - Jama, 2021 - jamanetwork.com
Importance Thrombotic events are commonly reported in critically ill patients with COVID-19.
Limited data exist to guide the intensity of antithrombotic prophylaxis. Objective To evaluate …

Intermediate-dose versus standard-dose prophylactic anticoagulation in patients with COVID-19 admitted to the intensive care unit: 90-day results from the …

B Bikdeli, AH Talasaz, F Rashidi… - Thrombosis and …, 2022 - thieme-connect.com
Background Thrombotic complications are considered among the main extrapulmonary
manifestations of coronavirus disease 2019 (COVID-19). The optimal type and duration of …

Impact of high-dose prophylactic anticoagulation in critically ill patients with COVID-19 pneumonia

C Tacquard, A Mansour, A Godon, J Godet, J Poissy… - Chest, 2021 - Elsevier
Background Because of the high risk of thrombotic complications (TCs) during SARS-CoV-2
infection, several scientific societies have proposed to increase the dose of preventive …

Therapeutic anticoagulation in critically ill patients with Covid-19–preliminary report

REMAP-CAP, ACTIV-4a, ATTACC Investigators… - MedRxiv, 2021 - medrxiv.org
Background Thrombosis may contribute to morbidity and mortality in Covid-19. We
hypothesized that therapeutic anticoagulation would improve outcomes in critically ill …

American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: May 2021 update on the use of …

A Cuker, EK Tseng, R Nieuwlaat… - Blood …, 2021 - ashpublications.org
Abstract Background: COVID-19–related critical illness is associated with an increased risk
of venous thromboembolism (VTE). Objective: These evidence-based guidelines of the …

Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with COVID-19: a systematic review and meta …

L Ortega-Paz, M Galli, D Capodanno… - European Heart …, 2022 - academic.oup.com
Background The clinical impact of different prophylactic anticoagulation regimens among
hospitalized patients with coronavirus disease 2019 (COVID-19) remains unclear. We …

Higher anticoagulation targets and risk of thrombotic events in severe COVID-19 patients: bi-center cohort study

J Helms, F Severac, H Merdji, M Schenck… - Annals of intensive …, 2021 - Springer
Background Thromboprophylaxis of COVID-19 patients is a highly debated issue. We aimed
to compare the occurrence of thrombotic/ischemic events in COVID-19 patients with acute …

Intermediate versus standard-dose prophylactic anticoagulation and statin therapy versus placebo in critically-ill patients with COVID-19: Rationale and design of the …

B Bikdeli, AH Talasaz, F Rashidi, B Sharif-Kashani… - Thrombosis research, 2020 - Elsevier
Background Microvascular and macrovascular thrombotic events are among the hallmarks
of coronavirus disease 2019 (COVID-19). Furthermore, the exuberant immune response is …

Randomized trial of anticoagulation strategies for noncritically ill patients hospitalized with COVID-19

GW Stone, ME Farkouh, A Lala, E Tinuoye… - Journal of the American …, 2023 - jacc.org
Background Prior studies of therapeutic-dose anticoagulation in patients with COVID-19
have reported conflicting results. Objectives We sought to determine the safety and …

Different anticoagulant regimens, mortality, and bleeding in hospitalized patients with COVID-19: a systematic review and an updated meta-analysis

R Parisi, S Costanzo, A Di Castelnuovo… - … in thrombosis and …, 2021 - thieme-connect.com
We conducted a systematic review and a meta-analysis to assess the association of
anticoagulants and their dosage with in-hospital all-cause mortality in COVID-19 patients …