Young COVID-19 patients show a higher degree of microglial activation when compared to controls

J Matschke, H Lahann, S Krasemann… - Frontiers in …, 2022 - frontiersin.org
The severe acute respiratory syndrome-corona virus type 2 (SARS-CoV-2) is the cause of
human coronavirus disease 2019 (COVID-19). Since its identification in late 2019 SARS …

[HTML][HTML] Role of microglia, decreased neurogenesis and oligodendrocyte depletion in long COVID-mediated brain impairments

ZYD Wei, K Liang, AK Shetty - Aging and Disease, 2023 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a recent
worldwide coronavirus disease-2019 (COVID-19) pandemic. SARS-CoV-2 primarily causes …

[HTML][HTML] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and glial cells: Insights and perspectives

G Vargas, LHM Geraldo, NG Salomão, MV Paes… - Brain, behavior, & …, 2020 - Elsevier
In December 2019, a pneumonia outbreak was reported in Wuhan, Hubei province, China.
Since then, the World Health Organization declared a public health emergency of …

The link between SARS-CoV-2 related microglial reactivity and astrocyte pathology in the inferior olivary nucleus

N Madden, YZJ Mei, K Jakubiak, J Li… - Frontiers in …, 2023 - frontiersin.org
The pathological involvement of the central nervous system in SARS-CoV2 (COVID-19)
patients is established. The burden of pathology is most pronounced in the brain stem …

Microglia fighting for neurological and mental health: on the central nervous system frontline of COVID-19 pandemic

E Goncalves de Andrade, E Šimončičová… - Frontiers in Cellular …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is marked by cardio-respiratory alterations, with
increasing reports also indicating neurological and psychiatric symptoms in infected …

COVID‐19‐related neuropathology and microglial activation in elderly with and without dementia

TE Poloni, V Medici, M Moretti, SD Visonà… - Brain …, 2021 - Wiley Online Library
The actual role of SARS‐CoV‐2 in brain damage remains controversial due to lack of
matched controls. We aim to highlight to what extent is neuropathology determined by SARS …

Neuropathology in COVID-19 autopsies is defined by microglial activation and lesions of the white matter with emphasis in cerebellar and brain stem areas

JA Stein, M Kaes, S Smola… - Frontiers in …, 2023 - frontiersin.org
Introduction This study aimed to investigate microglial and macrophage activation in 17
patients who died in the context of a COVID-19 infection in 2020 and 2021. Methods …

Microglial Inflammatory Responses to SARS‐CoV‐2 Infection: A Comprehensive Review

R Dey, B Bishayi - Cellular and Molecular Neurobiology, 2024 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is primarily a respiratory disease causing a
worldwide pandemic in the year of 2019. SARS‐CoV‐2 is an enveloped, positive-stranded …

SARS-CoV-2 infection of microglia elicits proinflammatory activation and apoptotic cell death

GU Jeong, J Lyu, KD Kim, YC Chung… - Microbiology …, 2022 - Am Soc Microbiol
Accumulating evidence suggests that severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection causes various neurological symptoms in patients with coronavirus …

Cellular and molecular effects of SARS-CoV-2 linking lung infection to the brain

L Francistiová, A Klepe, G Curley, K Gulya… - Frontiers in …, 2021 - frontiersin.org
In December 2019, a new viral disease emerged and quickly spread all around the world. In
March 2020, the COVID-19 outbreak was classified as a global pandemic and by June …