All-in-one detection of breast cancer-derived exosomal miRNA on a pen-based paper chip

S Guo, H Xie, X Zhao, H He, X Feng, Y Li, BF Liu… - Analyst, 2024 - pubs.rsc.org
Exosomal microRNAs (miRNAs) play a pivotal role in intercellular communication,
regulating gene expression in target cells, and hold significant promise as cancer …

A label-free activatable biosensor for in situ detection of exosomal microRNAs based on DNA-AgNCs and hairpin type nucleic acid probes

D Li, QW Li, H Xiang, SS Yuan, XP Yang - Analytical Methods, 2024 - pubs.rsc.org
Exosomal microRNA (miRNA) is a potential biomarker for cancer diagnosis, metastasis, and
treatment. In situ detection of exosomal miRNA is an attractive option due to its simplicity and …

In situ multiplex detection of serum exosomal microRNAs using an all-in-one biosensor for breast cancer diagnosis

H Wang, D He, K Wan, X Sheng, H Cheng, J Huang… - Analyst, 2020 - pubs.rsc.org
Herein, a simple all-in-one biosensor based on a DNA three-way junction has been
constructed for in situ simultaneous detection of multiple miRNAs by competitive strand …

Janus wireframe DNA cube-based 3D nanomachine for rapid and stable fluorescence detection of exosomal microRNA

Y Xu, X Li, C Niu, H Wu, Y Yong, C Qi, W Gong… - Biosensors and …, 2022 - Elsevier
Exosomal microRNAs (miRNAs) have been demonstrated to be credible biomarkers for the
diagnosis and monitoring of tumors. Nevertheless, developing simple, rapid, and stable …

All-in-one nanoflare biosensor combined with catalyzed hairpin assembly amplification for in situ and sensitive exosomal miRNA detection and cancer classification

XW Zhang, L Du, MX Liu, JH Wang, S Chen, YL Yu - Talanta, 2024 - Elsevier
Exosomal miRNAs can reflect tumor progression and metastasis, and are effective
biomarkers for cancer diagnosis. However, the accuracy of exosomal miRNA-based cancer …

Carbon nanotube field-effect transistor biosensor for ultrasensitive and label-free detection of breast cancer exosomal miRNA21

T Li, Y Liang, J Li, Y Yu, MM Xiao, W Ni… - Analytical …, 2021 - ACS Publications
Tumor-derived exosomal miRNAs may have important functions in the onset and
progression of cancers and are potential biomarkers for early diagnosis and prognosis …

An in situ exosomal miRNA sensing biochip based on multi-branched localized catalytic hairpin assembly and photonic crystals

T Wu, X Liu, H Chen, Y Liu, Y Cao - Biosensors and Bioelectronics, 2023 - Elsevier
Exosomal microRNAs (miRNAs) are emerging as attractive non-invasive and reliable
biomarkers for disease diagnosis. In situ exosomal miRNA detection can avoid laborious …

Sensitive fluorescent detection of exosomal microRNA based on enzymes-assisted dual-signal amplification

Y Xia, Z Huang, T Chen, L Xu, G Zhu, W Chen… - Biosensors and …, 2022 - Elsevier
The analysis of microRNAs (miRNAs) in exosomes offers significant information for a rapid
and non-invasive diagnosis of cancer. However, the clinical utility of miRNAs as biomarkers …

Rapid electrochemical biosensor for sensitive profiling of exosomal microRNA based on multifunctional DNA tetrahedron assisted catalytic hairpin assembly

Y Zhang, X Zhang, B Situ, Y Wu, S Luo, L Zheng… - Biosensors and …, 2021 - Elsevier
Profiling of exosomal microRNA (exo-miRNA) is very important for cancer diagnosis and
treatment. However, rapid and sensitive determination the trace of exo-miRNA in clinical …

In situ single step detection of exosome microRNA using molecular beacon

JH Lee, JA Kim, MH Kwon, JY Kang, WJ Rhee - Biomaterials, 2015 - Elsevier
In situ single step detection of microRNAs (miRNA) in a whole exosome has been
developed as a novel diagnosis method that can be utilized for various diseases. Exosomes …