Premature ovarian insufficiency: new perspectives on genetic cause and phenotypic spectrum

EJ Tucker, SR Grover, A Bachelot, P Touraine… - Endocrine …, 2016 - academic.oup.com
Premature ovarian insufficiency (POI) is one form of female infertility, defined by loss of
ovarian activity before the age of 40 and characterized by amenorrhea (primary or …

Genetics of primary ovarian insufficiency

R Rossetti, I Ferrari, M Bonomi, L Persani - Clinical genetics, 2017 - Wiley Online Library
Primary ovarian insufficiency (POI) is characterized by a loss of ovarian function before the
age of 40 and account for one major cause of female infertility. POI relevance is continuously …

[HTML][HTML] Current understanding of the etiology, symptomatology, and treatment options in premature ovarian insufficiency (POI)

B Ishizuka - Frontiers in endocrinology, 2021 - frontiersin.org
Premature ovarian insufficiency (POI) occurs in at least 1% of all women and causes life-
long health problems and psychological stress. Infertility caused by POI used to be …

[HTML][HTML] Premature ovarian insufficiency: past, present, and future

SJ Chon, Z Umair, MS Yoon - Frontiers in cell and developmental …, 2021 - frontiersin.org
Premature ovarian insufficiency (POI) is the loss of normal ovarian function before the age of
40 years, a condition that affects approximately 1% of women under 40 years old and 0.1 …

Recent advances in the study of genes involved in non-syndromic premature ovarian failure

P Laissue, G Vinci, RA Veitia, M Fellous - Molecular and Cellular …, 2008 - Elsevier
Premature ovarian failure (POF) is a common pathology leading to infertility affecting about
1% of women under 40 years old. In POF patients, the ovarian dysfunction is characterized …

Current concepts in premature ovarian insufficiency

K Maclaran, N Panay - Women's health, 2015 - journals.sagepub.com
Premature ovarian insufficiency (POI) is a life-changing diagnosis, with profound physical
and psychological consequences. Unfortunately, there are many deficiencies in our …

Primary ovarian insufficiency

JSE Laven - Seminars in reproductive medicine, 2016 - thieme-connect.com
Primary ovarian insufficiency (POI), also known as premature ovarian failure or premature
menopause, is defined as cessation of menstruation before the expected age of …

Premature ovarian insufficiency: phenotypic characterization within different etiologies

X Jiao, H Zhang, H Ke, J Zhang, L Cheng… - The Journal of …, 2017 - academic.oup.com
Context: Premature ovarian insufficiency (POI) is highly heterogeneous, both in phenotype
and etiology. They are not yet clearly stated and correlated. Objective: To characterize …

The genetics of premature ovarian failure: current perspectives

C Chapman, L Cree, AN Shelling - International journal of women's …, 2015 - Taylor & Francis
Premature ovarian failure (POF) is a common cause of infertility in women, characterized by
amenorrhea, hypoestrogenism, and elevated gonadotropin levels in women under the age …

Molecular genetics of premature ovarian insufficiency

X Jiao, H Ke, Y Qin, ZJ Chen - Trends in Endocrinology & Metabolism, 2018 - cell.com
Premature ovarian insufficiency (POI) is highly heterogeneous in genetic etiology. Yet
identifying causative genes has been challenging with candidate gene approaches. Recent …