Identification of the nucleotide sequence of the lipoprotein lipase gene as well as its role in the development of hyperlipidemia and pancreatitis in the Miniature …

R Schickel - 2005 - edoc.ub.uni-muenchen.de
Lipoprotein Lipase (LPL) is a key enzyme in lipid transport. It catalyses the hydrolysis of the
triacylglycerol component of chylomicrons and very low-density lipoproteins (VLDL) …

Lipoprotein lipase: recent contributions from molecular biology

J Auwerx, P Leroy, K Schoonjans - Critical reviews in clinical …, 1992 - Taylor & Francis
Lipoprotein lipase (LPL) is a glycoprotein enzyme that is produced in several cells and
tissues. LPL belongs to a large lipase gene family that includes, among others, hepatic …

Lipid and lipoprotein analysis of cats with lipoprotein lipase deficiency

Ginzinger, Clee, Dallongeville, Lewis… - European journal of …, 1999 - Wiley Online Library
Background We have previously described a colony of domestic cats with a naturally
occurring mutation in the lipoprotein lipase (LPL) gene. We have now further characterized …

Lipoprotein lipase deficiency with pancreatitis in mink: biochemical characterization and pathology

B Christophersen, K Nordstoga, Y Shen… - Journal of lipid …, 1997 - ASBMB
A severe hyperlipemia in mink, with a pattern that suggested recessive inheritance, was
observed at a farm in Norway. On a normal mink diet, affected animals had grossly elevated …

A mutation in the lipoprotein lipase gene is the molecular basis of chylomicronemia in a colony of domestic cats.

DG Ginzinger, ME Lewis, Y Ma… - The Journal of …, 1996 - Am Soc Clin Investig
Members of a domestic cat colony with chylomicronemia share many phenotypic features
with human lipoprotein lipase (LPL) deficiency. Biochemical analysis reveals that these cats …

Homozygosity for a mutation in the lipoprotein lipase gene (Gly139→Ser) causes chylomicronaemia in a boy of Spanish descent

SM Bijvoet, T Bruin, S Thzgöl, HD Bakker, MR Hayden… - Human genetics, 1994 - Springer
The enzyme lipoprotein lipase (LPL) plays a crucial role in triglyceride metabolism through
catalysis of triglyceride-rich chylomicrons and very low density lipoproteins. Primary LPL …

A mutation in the lipoprotein lipase gene associated with hyperlipoproteinemia type I in mink: studies on lipid and lipase levels in heterozygotes.

A Lindberg, K Nordstoga… - International …, 1998 - spandidos-publications.com
Severe hypertriglyceridemia was previously observed in mink. Affected animals had no
detectable lipoprotein lipase activity, but normal amounts of lipoprotein lipase protein in post …

Lipoprotein lipase: a multifunctional enzyme in lipoprotein metabolism

L Foubert, P Benlian, G Turpin - Presse Medicale (Paris, France …, 1996 - europepmc.org
Lipoprotein lipase (LPL) is a rate-limiting enzyme for the hydrolysis of triglycerides. Recently
new insights into non-enzymatic functions have emerged. Complete lipoprotein lipase …

Lipoprotein lipase deficiencies

J Etienne, D Brault - Annales de Biologie Clinique, 1992 - europepmc.org
Lipoprotein lipase (LPL) is an enzyme which plays a major role in the metabolism of
circulating triglyceride-rich lipoproteins. It hydrolyzes chylomicron and VLDL triglycerides …

Characterization of a lipoprotein lipase class III type defect in hypertriglyceridemic cats.

LN Peritz, JD Brunzell, C Harvey-Clarke… - … Medecine Clinique et …, 1990 - europepmc.org
Lipoprotein lipase (LPL) is an important enzyme involved in triacylglycerol metabolism in
plasma. We have characterized the deficiency in LPL activity in hypertriglyceridemic cats …