Classic Signaling Pathways in Alveolar Injury and Repair Involved in Sepsis‐Induced ALI/ARDS: New Research Progress and Prospect

W Li, D Li, Y Chen, H Abudou, H Wang, J Cai… - Disease …, 2022 - Wiley Online Library
Sepsis is a common critical clinical disease with high mortality that can cause approximately
10 million deaths worldwide each year. Acute lung injury (ALI) or acute respiratory distress …

[HTML][HTML] Acute lung injury caused by sepsis: how does it happen?

B Sun, M Lei, J Zhang, H Kang, H Liu, F Zhou - Frontiers in Medicine, 2023 - frontiersin.org
Sepsis is a systemic inflammatory disease caused by severe infections that involves multiple
systemic organs, among which the lung is the most susceptible, leaving patients highly …

Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies

S Luh, C Chiang - Journal of Zhejiang University Science B, 2007 - Springer
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS), which manifests as non-
cardiogenic pulmonary edema, respiratory distress and hypoxemia, could be resulted from …

[HTML][HTML] Integrating molecular pathogenesis and clinical translation in sepsis-induced acute respiratory distress syndrome

JA Englert, C Bobba, RM Baron - JCI insight, 2019 - ncbi.nlm.nih.gov
Sepsis-induced acute respiratory distress syndrome (ARDS) has high morbidity and
mortality and arises after lung infection or infection at extrapulmonary sites. An aberrant host …

The role of macrophages in the pathogenesis of ALI/ARDS

X Huang, H Xiu, S Zhang, G Zhang - Mediators of inflammation, 2018 - Wiley Online Library
Despite development in the understanding of the pathogenesis of acute lung injury
(ALI)/acute respiratory distress syndrome (ARDS), the underlying mechanism still needs to …

Models and mechanisms of acute lung injury caused by direct insults

LK Reiss, U Uhlig, S Uhlig - European journal of cell biology, 2012 - Elsevier
Acute lung injury (ALI) and its more severe form acute respiratory distress syndrome (ARDS)
are life-threatening diseases that are characterized by acute onset, pulmonary inflammation …

[HTML][HTML] Regulation of alveolar macrophage death in acute lung inflammation

EKY Fan, J Fan - Respiratory research, 2018 - Springer
Acute lung injury (ALI) and its severe form, known as acute respiratory distress syndrome
(ARDS), are caused by direct pulmonary insults and indirect systemic inflammatory …

[HTML][HTML] Repair after acute lung injury: molecular mechanisms and therapeutic opportunities

A González-López, GM Albaiceta - Critical Care, 2012 - Springer
Acute lung injury (ALI) is a clinical syndrome characterized by impairment in gas exchange
and/or lung mechanics that leads to hypoxemia and increased work of breathing (WOB) …

[PDF][PDF] Mechanisms of alveolar epithelial repair in acute lung injury-a translational approach

T Geiser - Swiss medical weekly, 2003 - smw.ch
In patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS),
extensive damage to the alveolar epithelial and endothelial barrier is observed, resulting in …

Role of the pulmonary epithelium and inflammatory signals in acute lung injury

AM Manicone - Expert review of clinical immunology, 2009 - Taylor & Francis
Acute lung injury (ALI) is a clinical disease marked by respiratory failure due to disruption of
the epithelial and endothelial barrier, flooding of the alveolar compartment with protein-rich …