Here, we summarize the literature relevant to recent advances in three‐dimensional (3D)
histopathology in relation to clinical oncology, highlighting serial sectioning, tissue clearing …

Imaging is vital for the assessment of physiologic and phenotypic details. In the past,
biomedical imaging was heavily reliant on analog, low-throughput methods, which would …

Recent advances in 3D pathology offer the ability to image orders of magnitude more tissue
than conventional pathology methods while also providing a volumetric context that is not …

High-throughput methods for slide-free three-dimensional (3D) pathological analyses of
whole biopsies and surgical specimens offer the promise of modernizing traditional …

In recent years, there has been a revived appreciation for the importance of spatial context
and morphological phenotypes for both understanding disease progression and guiding …

The role of pathology in patient management has evolved over time from the retrospective
review of cells, tissue, and disease ('what happened') to a prospective outlook ('what will …

Significant advances in investigative pathology historically have been triggered by the
development of new research tools. For example, new histochemical staining techniques in …

Objective. In the era of precision medicine, human tumor atlas-oriented studies have been
significantly facilitated by high-resolution, multi-modal tissue based microscopic pathology …

With the rapid advancement in large-throughput scanning technologies, digital pathology
has emerged as platform with promise for diagnostic approaches, but also for high …

Abstract Three-dimensional (3D) imaging is increasingly being incorporated into a variety of
medical specialties: surgery and radiology being but two prominent examples. Image …