Multidimensional functional and structural evaluation reveals neuroretinal impairment in early diabetic retinopathy

KA Joltikov, VM de Castro, JR Davila… - … & visual science, 2017 - iovs.arvojournals.org
Purpose: To test whether quantitative functional tests and optical coherence tomography
(OCT)-defined structure can serve as effective tools to diagnose and monitor early diabetic …

Is neuronal dysfunction an early sign of diabetic retinopathy? Microperimetry and spectral domain optical coherence tomography (SD-OCT) study in individuals with …

A Verma, PK Rani, R Raman, SS Pal, G Laxmi… - Eye, 2009 - nature.com
Purpose To elucidate changes in the neurosensory retina in the macular area, using
spectral domain OCT and correlate with functional loss on fundus-related microperimetry, in …

Disorganization of retinal inner layers (DRIL) and neuroretinal dysfunction in early diabetic retinopathy

KA Joltikov, CA Sesi, VM de Castro… - … & visual science, 2018 - iovs.arvojournals.org
Purpose: To elucidate the relationship between disorganization of retinal inner layers
(DRILs) and retinal function in diabetic patients without diabetic retinopathy (DR) and with …

Approach for a clinically useful comprehensive classification of vascular and neural aspects of diabetic retinal disease

MD Abramoff, PE Fort, IC Han… - … & visual science, 2018 - iovs.arvojournals.org
Abstract The Early Treatment Diabetic Retinopathy Study (ETDRS) and other standardized
classification schemes have laid a foundation for tremendous advances in the …

Structural neurodegeneration correlates with early diabetic retinopathy

U Frydkjaer-Olsen, RS Hansen, T Peto… - International …, 2018 - Springer
Purpose To examine differences in structural and functional neurodegenerative
measurements between patients with no and early diabetic retinopathy (DR). Methods In this …

Functional and structural findings of neurodegeneration in early stages of diabetic retinopathy: cross-sectional analyses of baseline data of the EUROCONDOR …

AR Santos, L Ribeiro, F Bandello, R Lattanzio… - Diabetes, 2017 - Am Diabetes Assoc
This cross-sectional study evaluated the relationship between 1) functional and structural
measurements of neurodegeneration in the initial stages of diabetic retinopathy (DR) and 2) …

Early neurodegeneration of the inner retinal layers in type 1 diabetes mellitus

FC Gundogan, F Akay, S Uzun, U Yolcu, E Çağıltay… - …, 2016 - karger.com
Purpose: This study explores retinal structural changes in type 1 diabetes without clinically
diagnosed diabetic retinopathy (DR). Methods: Peripapillary retinal nerve fiber layer (RNFL) …

Diabetic retinopathy: recent advances towards understanding neurodegeneration and vision loss

AJ Barber - Science China Life Sciences, 2015 - Springer
Diabetic retinopathy (DR) is one of the most common retinal diseases world-wide. It has a
complex pathology that involves the vasculature of the inner retina and breakdown of the …

Neurodegeneration in diabetic retinopathy: does it really matter?

R Simó, AW Stitt, TW Gardner - Diabetologia, 2018 - Springer
The concept of diabetic retinopathy as a microvascular disease has evolved, in that it is now
considered a more complex diabetic complication in which neurodegeneration plays a …

Evidence for structural and functional damage of the inner retina in diabetes with no diabetic retinopathy

G Montesano, G Ometto, BE Higgins… - … & visual science, 2021 - iovs.arvojournals.org
Purpose: To provide structural and functional evidence of inner retinal loss in diabetes prior
to vascular changes and interpret the structure-function relationship in the context of an …