Spatiotemporal dynamics of virus infection spreading in tissues

G Bocharov, A Meyerhans, N Bessonov, S Trofimchuk… - PLoS …, 2016 - journals.plos.org
Virus spreading in tissues is determined by virus transport, virus multiplication in host cells
and the virus-induced immune response. Cytotoxic T cells remove infected cells with a rate …

Interplay between reaction and diffusion processes in governing the dynamics of virus infections

G Bocharov, A Meyerhans, N Bessonov… - Journal of Theoretical …, 2018 - Elsevier
Spreading of viral infection in the tissues such as lymph nodes or spleen depends on virus
multiplication in the host cells, their transport and on the immune response. Reaction …

Modelling the dynamics of virus infection and immune response in space and time

G Bocharov, A Meyerhans, N Bessonov… - … Journal of Parallel …, 2019 - Taylor & Francis
Spreading of viral infection in the tissues such as lymph nodes or spleen depends on virus
multiplication in the host cells, their transport and on the immune response. Reaction …

Infection spreading in cell culture as a reaction-diffusion wave

LA Mahiout, N Bessonov, B Kazmierczak… - ESAIM: Mathematical …, 2022 - esaim-m2an.org
Infection spreading in cell culture occurs due to virus replication in infected cells and its
random motion in the extracellular space. Multiplicity of infection experiments in cell cultures …

Effects of diffusion and delayed immune response on dynamic behavior in a viral model

HY Alfifi - Applied Mathematics and Computation, 2023 - Elsevier
This paper studies a diffusive viral infection system with delayed immune response in the
one-domain system. A system of DDE equations was explored, both analytically and …

[HTML][HTML] Viral diffusion and cell-to-cell transmission: mathematical analysis and simulation study

H Shu, Z Ma, XS Wang, L Wang - Journal de Mathématiques Pures et …, 2020 - Elsevier
We propose a general model to investigate the joint impact of viral diffusion and cell-to-cell
transmission on viral dynamics. The mathematical challenge lies in the fact that the model …

Modeling the effect of non-cytolytic immune response on viral infection dynamics in the presence of humoral immunity

M Dhar, S Samaddar, P Bhattacharya - Nonlinear Dynamics, 2019 - Springer
In this paper, a mathematical model describing the viral infection dynamics with non-cytolytic
effect of humoral immune response is presented and analyzed. The effect of non-cytolytic …

Mathematical modeling of viral infection dynamics in spherical organs

R Dunia, R Bonnecaze - Journal of mathematical biology, 2013 - Springer
A general mathematical model of viral infections inside a spherical organ is presented.
Transported quantities are used to represent external cells or viral particles that penetrate …

Viral infection model with diffusion and state-dependent delay: stability of classical solutions

A Rezounenko - arXiv preprint arXiv:1706.08620, 2017 - arxiv.org
A class of reaction-diffusion virus dynamics models with intracellular state-dependent delay
and a general non-linear infection rate functional response is investigated. We are …

The spatial dynamics of immune response upon virus infection through hybrid dynamical computational model

Y Cai, Z Zhao, C Zhuge - Frontiers in Immunology, 2023 - frontiersin.org
Introduction The immune responses play important roles in the course of disease initiation
and progression upon virus infection such as SARS-CoV-2. As the tissues consist of spatial …