Abstract Between 1-5: 100 people worldwide have never experienced normotypic vision due
to a condition called amblyopia, and about 1: 4000 suffer from inherited retinal dystrophies …

Brain plasticity refers to the ability of synaptic connections to adapt their function and
structure in response to experience, including environmental changes, sensory deprivation …

Experience-dependent plasticity is closely linked with the development of sensory function.
Beyond this sensitive period, developmental plasticity is actively limited; however, new …

Over the last 50 years, research into the developmental plasticity of the visual cortex has led
to a growing understanding of first the causes and then of the underlying cellular …

Highlights•Congenital cataract reversal individuals reveal sensitive periods in human brain
development.•Striate cortex recovers to a larger degree than extrastriate cortex after sight …

Early blindness causes fundamental alterations of neural function across more than 25% of
cortex—changes that span the gamut from metabolism to behavior and collectively …

The aim of this review is to discuss the existing evidence supporting different processes of
visual brain plasticity after early damage, as opposed to damage that occurs during …

The'bionic eye'—so long a dream of the future—is finally becoming a reality with retinal
prostheses available to patients in both the US and Europe. However, clinical experience …

Plasticity in the human and animal brain is the rule, the base for development, and the way
to deal effectively with the environment for making the most efficient use of all the senses …

Citation information: Astle AT, Webb BS & McGraw PV. Can perceptual learning be used to
treat amblyopia beyond the critical period of visual development? Ophthalmic Physiol Opt …