Adjuvants and delivery systems based on polymeric nanoparticles for mucosal vaccines

Z Jin, S Gao, X Cui, D Sun, K Zhao - International journal of pharmaceutics, 2019 - Elsevier
Most pathogens enter the body through mucosal surfaces. Therefore, vaccination through
the mucosal route can greatly enhance the mucosal immune response. Vaccination via the …

Polymer nanotechnology based approaches in mucosal vaccine delivery: challenges and opportunities

R Sharma, U Agrawal, N Mody, SP Vyas - Biotechnology advances, 2015 - Elsevier
Mucosal sites serve as the main portal for the entry of pathogens and thus immunization
through mucosal routes can greatly improve the immunity. Researchers are continuously …

[HTML][HTML] Nano and microparticles as potential oral vaccine carriers and adjuvants against infectious diseases

SD Jazayeri, HX Lim, K Shameli, SK Yeap… - Frontiers in …, 2021 - frontiersin.org
Mucosal surfaces are the first site of infection for most infectious diseases and oral
vaccination can provide protection as the first line of defense. Unlike systemic …

Implication of nanoparticles/microparticles in mucosal vaccine delivery

SP Vyas, PN Gupta - Expert review of vaccines, 2007 - Taylor & Francis
Although polymeric nanoparticles/microparticles are well established for the mucosal
administration of conventional drugs, they have not yet been developed commercially for …

[HTML][HTML] Applications of polymer-based nanoparticles in vaccine field

S Guo, D Fu, A Utupova, D Sun, M Zhou… - Nanotechnology …, 2019 - degruyter.com
Polymer-based nanoparticles have good solubility, stability, safety, and sustained release,
which increases the absorption of loaded drugs, protects the drugs from degradation, and …

Nanotechnology solutions for mucosal immunization

S Chadwick, C Kriegel, M Amiji - Advanced drug delivery reviews, 2010 - Elsevier
The current prevalence of infectious diseases in many developing regions of the world is a
serious burden, impacting both the general health as well as economic growth of these …

[HTML][HTML] Tailoring functional nanoparticles for oral vaccine delivery: recent advances and future perspectives

P Cao, ZP Xu, L Li - Composites Part B: Engineering, 2022 - Elsevier
The oral vaccine has attracted much interest due to easy administration, induction of local
and systemic immune responses, and pain relief. Nowadays, functional nanoparticles and …

[HTML][HTML] Polymer-based nanomaterials and applications for vaccines and drugs

J Han, D Zhao, D Li, X Wang, Z Jin, K Zhao - Polymers, 2018 - mdpi.com
Nanotechnology plays a significant role in drug development. As carriers, polymeric
nanoparticles can deliver vaccine antigens, proteins, and drugs to the desired site of action …

Nanoengineering of vaccines using natural polysaccharides

AS Cordeiro, MJ Alonso, M de la Fuente - Biotechnology advances, 2015 - Elsevier
Currently, there are over 70 licensed vaccines, which prevent the pathogenesis of around 30
viruses and bacteria. Nevertheless, there are still important challenges in this area, which …

Biodegradable nanoparticles as vaccine adjuvants and delivery systems: regulation of immune responses by nanoparticle-based vaccine

T Akagi, M Baba, M Akashi - Polymers in nanomedicine, 2012 - Springer
Polymeric nano-and microparticles have recently been shown to possess significant
potential as drug delivery systems. In particular, the use of biodegradable polymeric …