[HTML][HTML] Gut microbiota and metabolite alterations associated with reduced bone mineral density or bone metabolic indexes in postmenopausal osteoporosis

J He, S Xu, B Zhang, C Xiao, Z Chen, F Si, J Fu… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Reduced bone mineral density (BMD) is associated with an altered microbiota in senile
osteoporosis. However, the relationship among gut microbiota, BMD and bone metabolic …

The gut microbiome is altered in postmenopausal women with osteoporosis and osteopenia

EA Rettedal, BL Ilesanmi Oyelere… - Journal of Bone and …, 2021 - academic.oup.com
Osteoporosis and its precursor osteopenia are common metabolic bone diseases in
postmenopausal women. A growing body of evidence suggests that the gut microbiota is …

The association of gut microbiota with osteoporosis is mediated by amino acid metabolism: multiomics in a large cohort

C Ling, Z Miao, M Xiao, H Zhou, Z Jiang… - The Journal of …, 2021 - academic.oup.com
Context Several small studies have suggested that the gut microbiome might influence
osteoporosis, but there is little evidence from human metabolomics studies to explain this …

[HTML][HTML] Fecal and serum metabolomic signatures and microbial community profiling of postmenopausal osteoporosis mice model

K Wen, L Tao, Z Tao, Y Meng, S Zhou… - Frontiers in cellular …, 2020 - frontiersin.org
Background Multiple studies have shown that an imbalance in the intestinal microbiota is
related to bone metabolism, but the role of the intestinal microbiota in postmenopausal …

Gut microbiota alterations associated with reduced bone mineral density in older adults

M Das, O Cronin, DM Keohane, EM Cormac… - …, 2019 - academic.oup.com
Objective To investigate compositional differences in the gut microbiota associated with
bone homeostasis and fractures in a cohort of older adults. Methods Faecal microbiota …

Targeting the gut microbiota-related metabolites for osteoporosis: the inextricable connection of gut-bone axis

YW Zhang, Y Wu, XF Liu, X Chen, JC Su - Ageing research reviews, 2024 - Elsevier
Osteoporosis is a systemic skeletal disease characterized by decreased bone mass,
destruction of bone microstructure, raised bone fragility, and enhanced risk of fractures. The …

[HTML][HTML] High-throughput absolute quantification sequencing revealed osteoporosis-related gut microbiota alterations in Han Chinese elderly

M Wei, C Li, Y Dai, H Zhou, Y Cui, Y Zeng… - Frontiers in cellular …, 2021 - frontiersin.org
Objective Accumulative evidence suggests that gut microbiota play an important role in bone
remodeling and hence bone health maintenance. This study aimed to explore the …

Gut microbiota composition and bone mineral loss—epidemiologic evidence from individuals in Wuhan, China

C Li, Q Huang, R Yang, Y Dai, Y Zeng, L Tao… - Osteoporosis …, 2019 - Springer
We explored the association between gut microbiota composition and bone mineral loss in
Chinese elderly people by high-throughput 16S ribosomal RNA (rRNA) gene sequencing …

[HTML][HTML] Diversity analysis of gut microbiota in osteoporosis and osteopenia patients

J Wang, Y Wang, W Gao, B Wang, H Zhao, Y Zeng, Y Ji… - PeerJ, 2017 - peerj.com
Some evidence suggests that bone health can be regulated by gut microbiota. To better
understand this, we performed 16S ribosomal RNA sequencing to analyze the intestinal …

The gut microbiome and bone strength

M Castaneda, JM Strong, DA Alabi… - Current osteoporosis …, 2020 - Springer
Abstract Purpose of Review Osteoporosis is commonly diagnosed through the clinical
assessment of bone quantity using bone mineral density; however, the primary clinical …