Vascular calcification—new insights into its mechanism

SJ Lee, IK Lee, JH Jeon - International journal of molecular sciences, 2020 - mdpi.com
Vascular calcification (VC), which is categorized by intimal and medial calcification,
depending on the site (s) involved within the vessel, is closely related to cardiovascular …

Mechanisms and clinical consequences of vascular calcification

D Zhu, NCW Mackenzie, C Farquharson… - Frontiers in …, 2012 - frontiersin.org
Vascular calcification has severe clinical consequences and is considered an accurate
predictor of future adverse cardiovascular events, including myocardial infarction and stroke …

Vascular calcification: from pathophysiology to biomarkers

S Evrard, P Delanaye, S Kamel, JP Cristol, E Cavalier… - Clinica chimica acta, 2015 - Elsevier
The link between vascular calcification (VC) and increased mortality is now well established.
Over time, as clinical importance of this phenomenon has begun to be fully considered …

Vascular calcification in chronic kidney disease: diversity in the vessel wall

P Dube, A DeRiso, M Patel, D Battepati… - Biomedicines, 2021 - mdpi.com
Vascular calcification (VC) is one of the major causes of cardiovascular morbidity and
mortality in patients with chronic kidney disease (CKD). VC is a complex process expressing …

Inflammatory, metabolic, and genetic mechanisms of vascular calcification

LL Demer, Y Tintut - Arteriosclerosis, thrombosis, and vascular …, 2014 - Am Heart Assoc
This review centers on updating the active research area of vascular calcification. This
pathology underlies substantial cardiovascular morbidity and mortality, through adverse …

Molecular determinants of vascular calcification: a bench to bedside view

S Dellegrottaglie, J Sanz… - Current molecular …, 2006 - ingentaconnect.com
Vascular calcification (VC) is an orchestrated event, evoking the programmed process of the
osteogenesis and triggered by inflammatory cytokines active at vascular level. VC is a …

Vascular calcification and bone disease: the calcification paradox

V Persy, P D'Haese - Trends in molecular medicine, 2009 - cell.com
Vascular calcification or ectopic mineralization in blood vessels is an active, cell-regulated
process, increasingly recognized as a general cardiovascular risk factor. Remarkably …

Research models for studying vascular calcification

J Herrmann, M Babic, M Tölle, M van der Giet… - International journal of …, 2020 - mdpi.com
Calcification of the vessel wall contributes to high cardiovascular morbidity and mortality.
Vascular calcification (VC) is a systemic disease with multifaceted contributing and inhibiting …

Mechanistic insights into CKD-MBD-related vascular calcification and its clinical implications

R Kaur, R Singh - Life Sciences, 2022 - Elsevier
Abstract Chronic Kidney Disease (CKD) is linked to a rising prevalence of morbidity and
mortality primarily from cardiovascular complications and is considered a high or very high …

Vascular calcification: an update on mechanisms and challenges in treatment

M Wu, C Rementer, CM Giachelli - Calcified tissue international, 2013 - Springer
Vascular calcification is highly associated with cardiovascular disease mortality, particularly
in high-risk patients with diabetes and chronic kidney diseases (CKD). In blood vessels …