Since ancient times, even in today's modern world, infectious diseases cause lots of people to die. Infectious organisms, pathogens, cause diseases by physical interactions with human …
MD Dyer, C Neff, M Dufford, CG Rivera, D Shattuck… - PloS one, 2010 - journals.plos.org
Background Bacillus anthracis, Francisella tularensis, and Yersinia pestis are bacterial pathogens that can cause anthrax, lethal acute pneumonic disease, and bubonic plague …
X Yang, X Lian, C Fu, S Wuchty, S Yang… - Briefings in …, 2021 - academic.oup.com
While leading to millions of people's deaths every year the treatment of viral infectious diseases remains a huge public health challenge. Therefore, an in-depth understanding of …
Organisms are constantly exposed to microbial pathogens in their environments. When a pathogen meets its host, a series of intricate intracellular interactions shape the outcome of …
AF Brito, JW Pinney - Frontiers in microbiology, 2017 - frontiersin.org
To study virus–host protein interactions, knowledge about viral and host protein architectures and repertoires, their particular evolutionary mechanisms, and information on …
EA Franzosa, Y Xia - … of the National Academy of Sciences, 2011 - National Acad Sciences
General properties of the antagonistic biomolecular interactions between viruses and their hosts (exogenous interactions) remain poorly understood, and may differ significantly from …
Motivation: Infectious diseases such as malaria result in millions of deaths each year. An important aspect of any host-pathogen system is the mechanism by which a pathogen can …
V Navratil, B De Chassey, L Meyniel… - Nucleic acids …, 2009 - academic.oup.com
Infectious diseases caused by viral agents kill millions of people every year. The improvement of prevention and treatment of viral infections and their associated diseases …
Abstract Background Protein-protein interactions (PPIs) play a crucial role in initiating infection in a host-pathogen system. Identification of these PPIs is important for …