Network-based analysis of fatal comorbidities of COVID-19 and potential therapeutics
COVID-19 is a highly contagious disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The case-fatality rate is significantly higher in older patients …
coronavirus 2 (SARS-CoV-2). The case-fatality rate is significantly higher in older patients …
Interactome of SARS-CoV-2 modulated host proteins with computationally predicted PPIs: insights from translational systems biology studies
KB Karunakaran, N Balakrishnan… - Frontiers in Systems …, 2022 - frontiersin.org
Accelerated efforts to identify intervention strategies for the COVID-19 pandemic caused by
SARS-CoV-2 need to be supported by deeper investigations into host invasion and …
SARS-CoV-2 need to be supported by deeper investigations into host invasion and …
Pathway enrichment analysis of virus-host interactome and prioritization of novel compounds targeting the spike glycoprotein receptor binding domain–human …
SARS-CoV-2 has become a pandemic causing a serious global health concern. The
absence of effective drugs for treatment of the disease has caused its rapid spread on a …
absence of effective drugs for treatment of the disease has caused its rapid spread on a …
A systems biology approach identifies candidate drugs to reduce mortality in severely ill patients with COVID-19
Despite the availability of highly efficacious vaccines, coronavirus disease 2019 (COVID-19)
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lacks effective …
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lacks effective …
Unraveling the molecular crosstalk between Atherosclerosis and COVID-19 comorbidity
D Das, S Podder - Computers in biology and medicine, 2021 - Elsevier
Background Corona virus disease 2019 (COVID-19) caused by Severe Acute Respiratory
Syndrome Coronavirus− 2 (SARS-CoV-2) has created ruckus throughout the world. Growing …
Syndrome Coronavirus− 2 (SARS-CoV-2) has created ruckus throughout the world. Growing …
Network neighbors of viral targets and differentially expressed genes in COVID-19 are drug target candidates
The COVID-19 pandemic is raging. It revealed the importance of rapid scientific
advancement towards understanding and treating new diseases. To address this challenge …
advancement towards understanding and treating new diseases. To address this challenge …
[HTML][HTML] 3044 Cases reveal important prognosis signatures of COVID-19 patients
S Qin, W Li, X Shi, Y Wu, C Wang, J Shen… - Computational and …, 2021 - Elsevier
Critical patients and intensive care unit (ICU) patients are the main population of COVID-19
deaths. Therefore, establishing a reliable method is necessary for COVID-19 patients to …
deaths. Therefore, establishing a reliable method is necessary for COVID-19 patients to …
[HTML][HTML] Identifying potential drug targets and candidate drugs for COVID-19: biological networks and structural modeling approaches
G Selvaraj, S Kaliamurthi, GH Peslherbe… - F1000Research, 2021 - ncbi.nlm.nih.gov
Background: Coronavirus (CoV) is an emerging human pathogen causing severe acute
respiratory syndrome (SARS) around the world. Earlier identification of biomarkers for SARS …
respiratory syndrome (SARS) around the world. Earlier identification of biomarkers for SARS …
Unveiling COVID-19-associated organ-specific cell types and cell-specific pathway cascade
The novel coronavirus or COVID-19 has first been found in Wuhan, China, and became
pandemic. Angiotensin-converting enzyme 2 (ACE2) plays a key role in the host cells as a …
pandemic. Angiotensin-converting enzyme 2 (ACE2) plays a key role in the host cells as a …
A machine learning method for the identification and characterization of novel COVID-19 drug targets
In addition to vaccines, the World Health Organization sees novel medications as an urgent
matter to fight the ongoing COVID-19 pandemic. One possible strategy is to identify target …
matter to fight the ongoing COVID-19 pandemic. One possible strategy is to identify target …