The endolysin EFm1 from the E. faecalis 002 (002) phage IME-EF1 efficiently lyses E.
faecalis, a gram-positive bacterium that severely threatens human health. Here, the structure …

Enterococcus faecalis is increasingly becoming an important nosocomial infection
opportunistic pathogen. E. faecalis can easily obtain drug resistance, making it difficult to be …

Using bacteriophage-derived endolysins as an alternative strategy for fighting drug-resistant
bacteria has recently been garnering renewed interest. However, their application is still …

Due to the worldwide prevalence of antibiotic resistant strains, phages therapy has been
revitalized recently. In this study, an Enterococcus faecium phage named IME-EFm5 was …

Enterococcus faecalis is the primary species detected in cases of secondary persistent
infection resulting from root canal therapy failure. Due to the overuse of antibacterial agents …

Phage-derived lysins can hydrolyse bacterial cell walls and show great potential for
combating Gram-positive pathogens. In this study, the potential of LysEF-P10, a new lysin …

Phage-encoded endolysins are emerging antibacterial agents based on their ability to
efficiently degrade peptidoglycan on Gram-positive bacteria, but the envelope …

Bacteriophage endolysins degrade peptidoglycan and have been identified as antibacterial
candidates to combat antimicrobial resistance. Considering the catalytic and structural …

Bacteriophage-encoded endolysins have been identified as antibacterial candidates.
However, the development of endolysins as mainstream antibacterial agents first requires a …

Aims: In this work, we aimed to identify an effective treatment of infections caused by
Enterococcus spp. strains resistant to conventional antibiotics. Methods and Results: We …