[HTML][HTML] Drug discovery for parasitic diseases: powered by technology, enabled by pharmacology, informed by clinical science

SPS Rao, UH Manjunatha, S Mikolajczak… - Trends in …, 2023 - cell.com
While prevention is a bedrock of public health, innovative therapeutics are needed to
complement the armamentarium of interventions required to achieve disease control and …

Renewed strategies for drug development against parasitic diseases

HJ Vial, M Traore, AH Fairlamb, RG Ridley - Parasitology today, 1999 - cell.com
The conference reiterated the fact that most scientists involved in parasitology are involved
partly out of a desire to understand biological processes and partly out of a desire to make a …

[图书][B] Antiparasitic and antibacterial drug discovery: from molecular targets to drug candidates

PM Selzer - 2009 - books.google.com
Addressing parasitic diseases and those caused by bacteria, this much needed reference
and handbook provides a unique insight into the approach adopted by commercial science …

Drug discovery and development for neglected parasitic diseases

AR Renslo, JH McKerrow - Nature chemical biology, 2006 - nature.com
Diseases caused by tropical parasites affect hundreds of millions of people worldwide but
have been largely neglected for drug development because they affect poor people in poor …

Transgenic parasites accelerate drug discovery

A Rodriguez, RL Tarleton - Trends in parasitology, 2012 - cell.com
Parasitic neglected diseases are in dire need of new drugs either to replace old drugs
rendered ineffective because of resistance development, to cover clinical needs that had …

[HTML][HTML] Opportunities and challenges in antiparasitic drug discovery

R Pink, A Hudson, MA Mouriès, M Bendig - Nature reviews Drug …, 2005 - nature.com
New antiparasitic drugs are urgently needed to treat and control diseases such as malaria,
leishmaniasis, sleeping sickness and filariasis, which affect millions of people each year …

[HTML][HTML] Re-envisioning anti-apicomplexan parasite drug discovery approaches

GW Rangel, M Llinás - Frontiers in Cellular and Infection Microbiology, 2021 - frontiersin.org
Parasites of the phylum Apicomplexa impact humans in nearly all parts of the world, causing
diseases including to toxoplasmosis, cryptosporidiosis, babesiosis, and malaria …

[HTML][HTML] Antimalarial drug discovery—approaches and progress towards new medicines

EL Flannery, AK Chatterjee, EA Winzeler - Nature Reviews Microbiology, 2013 - nature.com
Malaria elimination has recently been reinstated as a global health priority but current
therapies seem to be insufficient for the task. Elimination efforts require new drug classes …

[HTML][HTML] Designing drugs for parasitic diseases of the developing world

JH McKerrow - PLoS Medicine, 2005 - journals.plos.org
Designing Drugs for Parasitic Diseases of the Developing World | PLOS Medicine Skip to main
content Advertisement PLOS Medicine Browse Current Issue Journal Archive Special Issues …

Anthelmintic discovery and development in the animal health industry

DJ Woods, C Lauret, T Geary - Expert opinion on drug discovery, 2007 - Taylor & Francis
Most modern anthelmintics used against human pathogens have come from the animal
health (AH) industry. Historically, new molecules were discovered empirically, but recent …