Hemolysis at low blood flow rates: in-vitro and in-silico evaluation of a centrifugal blood pump

M Schöps, SH Groß-Hardt, T Schmitz-Rode… - Journal of translational …, 2021 - Springer
Background Treating severe forms of the acute respiratory distress syndrome and cardiac
failure, extracorporeal membrane oxygenation (ECMO) has become an established …

[HTML][HTML] Computational fluid dynamics analysis and experimental hemolytic performance of three clinical centrifugal blood pumps: Revolution, Rotaflow and …

D Han, JL Leibowitz, L Han, S Wang, G He… - Medicine in novel …, 2022 - Elsevier
Centrifugal blood pumps have become popular for adult extracorporeal membrane
oxygenation (ECMO) due to their superior blood handling and reduced thrombosis risk …

Flow characteristics and hemolytic performance of the new Breethe centrifugal blood pump in comparison with the CentriMag and Rotaflow pumps

G He, J Zhang, A Shah, ZB Berk… - … Journal of Artificial …, 2021 - journals.sagepub.com
Blood pumps have been increasingly used in mechanically assisted circulation for
ventricular assistance and extracorporeal membrane oxygenation support or during …

[HTML][HTML] Blood pumps for extracorporeal membrane oxygenation: platelet activation during different operating conditions

F Fiusco, LM Broman, LP Wittberg - Asaio Journal, 2022 - journals.lww.com
Extracorporeal membrane oxygenation (ECMO) is a therapy used in severe
cardiopulmonary failure. Blood is pumped through an artificial circuit exposing it to …

Development of Design Methods of a Centrifugal Blood Pump with In Vitro Tests, Flow Visualization, and Computational Fluid Dynamics: Results inHemolysis Tests

K Takiura, T Masuzawa, S Endo, Y Wakisaka… - Artificial …, 1998 - Wiley Online Library
There are few established engineering guidelines aimed at reducing hemolysis for the
design of centrifugal blood pumps. In this study, a fluid dynamic approach was applied to …

Effect of blade curvature on the hemolytic and hydraulic characteristics of a centrifugal blood pump

C Ozturk, IB Aka, I Lazoglu - The International journal of …, 2018 - journals.sagepub.com
Aims: Impeller design has a significant impact on the overall performance of a blood pump.
In this study, the effect of the blade curvature was investigated by performing in silico and in …

Minimization of hemolysis in centrifugal blood pumps: influence of different geometries

H Schima, MR Müller, D Papantonis… - … Journal of Artificial …, 1993 - journals.sagepub.com
Centrifugal blood pumps are of substantial importance for intraoperative extracorporeal
circulation and for temporary cardiac assist. Their development and improvement raises …

On the optimization of a centrifugal maglev blood pump through design variations

P Wu, J Huo, W Dai, WT Wu, C Yin, S Li - Frontiers in physiology, 2021 - frontiersin.org
Centrifugal blood pumps are usually designed with secondary flow paths to avoid flow dead
zones and reduce the risk of thrombosis. Due to the secondary flow path, the intensity of …

A validated computational fluid dynamics model to estimate hemolysis in a rotary blood pump

A Arvand, M Hormes, H Reul - Artificial Organs, 2005 - Wiley Online Library
A major part of developing rotary blood pumps requires the optimization of hemolytic
properties of the entire pump. Application of a suited computational fluid dynamics (CFD) …

Computational modeling of the Food and Drug Administration's benchmark centrifugal blood pump

BC Good, KB Manning - Artificial organs, 2020 - Wiley Online Library
In order to simulate hemodynamics within centrifugal blood pumps and to predict pump
hemolysis, CFD simulations must be thoroughly validated against experimental data. They …