[HTML][HTML] Small-molecule antivirals treatment for COVID-19: A systematic review and network meta-analysis

B Zheng, Q Zhao, W Yang, P Feng, C Xin, Y Ying… - International Journal of …, 2024 - Elsevier
Objective This study aimed to explore the efficacy and safety of small-molecule antivirals for
treating coronavirus disease 2019 (COVID-19). Methods Seven databases were searched …

[HTML][HTML] Oral Molnupiravir and Nirmatrelvir/Ritonavir for the Treatment of COVID-19: A Literature Review with a Focus on Real-World Evidence

I Karniadakis, N Mazonakis, C Tsioutis… - Infectious Disease …, 2023 - mdpi.com
Vaccines remain the cornerstone of medical prevention and are highly effective in reducing
the risk of severe disease and death due to coronavirus disease 2019 (COVID-19). In the …

Recent progress of antiviral therapy for coronavirus disease 2019

M Zhao, J Zhang, H Li, Z Luo, J Ye, Y Xu… - European journal of …, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic has become a global public
health crisis, for which antiviral treatments are considered mainstream therapeutic …

Evaluation of oral small molecule drugs for the treatment of COVID-19 patients: a systematic review and network meta-analysis

Z Chen, F Tian - Annals of Medicine, 2023 - Taylor & Francis
Introduction At present, there are some randomized controlled trials (RCTs) of oral small
molecule drugs. The purpose of this study was to evaluate the efficacy and safety of oral …

The effect of antivirals on COVID-19: a systematic review

N Hussain, A Yoganathan, S Hewage… - Expert Review of Anti …, 2021 - Taylor & Francis
ABSTRACT Introduction Coronavirus Disease 2019 is a contagious infection that has
infected millions worldwide. The objective of this systematic review is to identify studies …

Comparative efficacy and safety of nirmatrelvir/ritonavir and molnupiravir for COVID‐19: A systematic review and meta‐analysis

B Amani, A Akbarzadeh, B Amani… - Journal of Medical …, 2023 - Wiley Online Library
This study aimed to compare the efficacy and safety of nirmatrelvir/ritonavir (Paxlovid) with
molnupiravir in the treatment of coronavirus disease 2019 (COVID‐19). To end this …

[HTML][HTML] The clinical efficacy and safety of anti-viral agents for non-hospitalized patients with COVID-19: a systematic review and network meta-analysis of randomized …

CC Lai, YH Wang, KH Chen, CH Chen, CY Wang - Viruses, 2022 - mdpi.com
This network meta-analysis compared the clinical efficacy and safety of anti-viral agents for
the prevention of disease progression among non-hospitalized patients with COVID-19 …

Molnupiravir and nirmatrelvir-ritonavir: oral coronavirus disease 2019 antiviral drugs

LD Saravolatz, S Depcinski… - Clinical Infectious …, 2023 - academic.oup.com
At a crucial time with rapid spread of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) Omicron variant globally, the United States Food and Drug Administration …

[HTML][HTML] Directly acting antivirals for COVID-19: where do we stand?

SL Teoh, YH Lim, NM Lai, SWH Lee - Frontiers in microbiology, 2020 - frontiersin.org
The outbreak of a novel coronavirus (SARS-CoV-2) in Wuhan, China in December 2019 has
now become a pandemic with no approved therapeutic agent. At the moment, the genomic …

Small-molecule antiviral agents in ongoing clinical trials for COVID-19

ÇB Apaydın, G Çınar, G Cihan-Üstündağ - Current drug targets, 2021 - ingentaconnect.com
The coronavirus disease 2019 (COVID-19) pandemic, due to the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in December 2019 and has …