Aging is known to be associated with an increased prevalence of multiple chronic diseases,
which frequently causes the use of complex therapeutic regimens. The aging process is …

Advancing age is characterized by impairment in the function of the many regulatory
processes that provide functional integration between cells and organs. Therefore, there …

Aging is characterized by a progressive loss of functional capacities of most if not all organs,
a reduction in homeostatic mechanisms, and a response to receptor stimulation. Also, loss of …

Aging is characterized by progressive impairment of functional capacities of all system
organs, reduction in homeostatic mechanisms, and altered response to receptor stimulation …

Ageing is characterized by a progressive decline in the functional reserve of multiple organs
and systems, which can influence drug disposition. In addition, comorbidity and …

Adverse drug events (ADEs) are all too common in older patients. Although there are
multiple causes for the ADEs in the elderly, alterations in pharmacokinetics (PK) and …

Introduction The proportion of the elderly is constantly increasing and by the year 2025 20%
of the population will be above 65 years of age. With advanced age, subjects will develop …

The population of older adults in the United States continues to expand, and the percentage
of patients with multiple comorbid disease states and complex drug regimens has increased …

Introduction: The worldwide population is aging, and several age-associated physiological
and pathophysiological changes can affect drug disposition. This is particularly important in …

Introduction Age-associated physiological changes can alter the disposition of drugs,
however, pathophysiological changes associated with geriatric syndromes in older adults …