Effectiveness of Paxlovid in reducing severe coronavirus disease 2019 and mortality in high-risk patients

R Najjar-Debbiny, N Gronich, G Weber… - Clinical Infectious …, 2023 - academic.oup.com
Background Paxlovid was granted an Emergency Use Authorization for the treatment of mild
to moderate coronavirus disease 2019 (COVID-19), based on the interim analysis of the …

[HTML][HTML] Paxlovid associated with decreased hospitalization rate among adults with COVID-19—United States, April–September 2022

MM Shah - MMWR. Morbidity and mortality weekly report, 2022 - cdc.gov
Among US adults diagnosed with COVID-19, including those with previous infection or
vaccination, persons who were prescribed Paxlovid within 5 days of diagnosis had a 51 …

[HTML][HTML] Efficacy and safety of Paxlovid in severe adult patients with SARS-Cov-2 infection: a multicenter randomized controlled study

J Liu, X Pan, S Zhang, M Li, K Ma, C Fan… - The Lancet Regional …, 2023 - thelancet.com
Summary Background Nirmatrelvir plus ritonavir (Paxlovid) reduced the risk of
hospitalization or death by 89% in high-risk, ambulatory adults with COVID-19. We aimed at …

[HTML][HTML] Safety and efficacy of Paxlovid against Omicron variants of coronavirus disease 2019 in elderly patients

C Weng, R Xie, G Han, Y Yuan, S Li, C Wang… - Infectious Diseases and …, 2023 - Springer
Introduction Elderly patients are the most affected and vulnerable to COVID-19 and effective
therapeutic interventions are urgently required. We clarified the safety and efficacy of …

Efficacy and safety of Paxlovid for COVID-19: a meta-analysis

Q Zheng, P Ma, M Wang, Y Cheng, M Zhou… - Journal of …, 2023 - journalofinfection.com
We read with interest the manuscript “Sensitivity and specificity of surveillance case
definitions in detection of influenza and respiratory syncytial virus among hospitalized …

An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug Resistance …, 2021 - Elsevier
The COVID-19 pandemic is one of the greatest threats to human health in the 21st century
with more than 257 million cases and over 5.17 million deaths reported worldwide (as of …

The future of Paxlovid for COVID-19

T Burki - The Lancet Respiratory Medicine, 2022 - thelancet.com
In comments to Bloomberg published on May 3, 2022, Pfizer chief executive officer Albert
Bourla suggested that patients who experience a relapse of symptoms after finishing a …

[HTML][HTML] Hospitalization and emergency department encounters for COVID-19 after paxlovid treatment—California, December 2021–May 2022

DE Malden - MMWR. Morbidity and mortality weekly report, 2022 - cdc.gov
Hospitalization and Emergency Department Encounters for COVID-19 After Paxlovid Treatment
— California, December 2021–May 2022 | MMWR Skip directly to site content Skip directly to …

Covid-19: Pfizer's paxlovid is 89% effective in patients at risk of serious illness, company reports

E Mahase - 2021 - bmj.com
Pfizer's oral antiviral drug paxlovid significantly reduces hospital admissions and deaths
among people with covid-19 who are at high risk of severe illness, when compared with …

[HTML][HTML] The emergence of powerful oral anti-COVID-19 drugs in the post-vaccine era

H Fan, F Lou, J Fan, M Li, Y Tong - The Lancet Microbe, 2022 - thelancet.com
The quest for effective drugs to treat COVID-19 has been a priority since the outbreak of the
disease. The clinical application of remdesivir has been greatly restricted by the need for …