Cardiovascular health and four epigenetic clocks

YH Lo, WY Lin - Clinical Epigenetics, 2022 - Springer
Background Cardiovascular health (CVH) was defined by the American Heart Association
as an integrative idealness of seven clinical or lifestyle factors. Based on populations of …

Association of cardiovascular health and epigenetic age acceleration

TD Pottinger, SS Khan, Y Zheng, W Zhang… - Clinical …, 2021 - Springer
Background Cardiovascular health (CVH) has been defined by the American Heart
Association (AHA) as the presence of the “Life's Simple 7” ideal lifestyle and clinical factors …

Prospective study of epigenetic age acceleration and incidence of cardiovascular disease outcomes in the ARIC study (Atherosclerosis Risk in Communities)

NS Roetker, JS Pankow, J Bressler… - Circulation: Genomic …, 2018 - Am Heart Assoc
Background: DNA methylation-based patterns of biological aging, known as epigenetic age
acceleration, are predictive of all-cause mortality, but little is known about their association …

Epigenetic clocks derived from western samples differentially reflect Taiwanese health outcomes

WY Lin - Frontiers in Genetics, 2023 - frontiersin.org
Introduction: Several epigenetic clocks have been developed, with five measures of
epigenetic age acceleration (EAA) especially receiving extensive investigations …

Healthy lifestyle, DNA methylation age acceleration, and incident risk of coronary heart disease

J Si, L Chen, C Yu, Y Guo, D Sun, Y Pang… - Clinical …, 2023 - Springer
Background DNA methylation clocks emerged as a tool to determine biological aging and
have been related to mortality and age-related diseases. Little is known about the …

[HTML][HTML] Higher diet quality relates to decelerated epigenetic aging

Y Kim, T Huan, R Joehanes, NM McKeown… - The American journal of …, 2022 - Elsevier
Background DNA methylation–based epigenetic age measures have been used as
biological aging markers and are associated with a healthy lifespan. Few population-based …

Cardiovascular health is associated with the epigenetic clock in the Berlin Aging Study II (BASE-II)

E Lemke, VM Vetter, N Berger, VL Banszerus… - Mechanisms of Ageing …, 2022 - Elsevier
The epigenetic clock parameter DNAm age acceleration is a promising biomarker of aging.
We have recently described an epigenetic clock based on only seven cytosine-phosphate …

An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease

S Horvath, M Gurven, ME Levine, BC Trumble… - Genome biology, 2016 - Springer
Background Epigenetic biomarkers of aging (the “epigenetic clock”) have the potential to
address puzzling findings surrounding mortality rates and incidence of cardio-metabolic …

Epigenetic age acceleration reflects long-term cardiovascular health

BT Joyce, T Gao, Y Zheng, J Ma, SJ Hwang… - Circulation …, 2021 - Am Heart Assoc
Rationale: Epigenetic aging is a novel measure of biological age, reflecting exposures and
disease risks independent of chronological age. It may serve as a useful biomarker of …

Accelerated DNA methylation age plays a role in the impact of cardiovascular risk factors on the human heart

CC Topriceanu, E Dev, M Ahmad, R Hughes… - Clinical …, 2023 - Springer
Background DNA methylation (DNAm) age acceleration (AgeAccel) and cardiac age by 12-
lead advanced electrocardiography (A-ECG) are promising biomarkers of biological and …