Potential role of tirzepatide towards Covid-19 infection in diabetic patients: a perspective approach

GES Batiha, HM Al-Kuraishy, AI Al-Gareeb… - …, 2023 - Springer
In Covid-19, variations in fasting blood glucose are considered a distinct risk element for a
bad prognosis and outcome in Covid-19 patients. Tirazepatide (TZT), a dual glucagon-like …

Anti‐inflammatory effects of sodium‐glucose cotransporter‐2 inhibitors in COVID‐19

H Yaribeygi, M Maleki, SL Atkin, P Kesharwani… - IUBMB …, 2023 - Wiley Online Library
The ongoing pandemic of COVID‐19 is intrinsically a systemic inflammatory disorder; hence,
those patients suffering an underlying chronic inflammatory disease such as diabetes …

Potential benefits and harms of novel antidiabetic drugs during COVID-19 crisis

M Mirabelli, E Chiefari, L Puccio, DP Foti… - International journal of …, 2020 - mdpi.com
Patients with diabetes have been reported to have enhanced susceptibility to severe or fatal
COVID-19 infections, including a high risk of being admitted to intensive care units with …

Can pioglitazone be potentially useful therapeutically in treating patients with COVID-19?

E Carboni, AR Carta, E Carboni - Medical Hypotheses, 2020 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a
pandemic disease (COVID-19) that has spread globally causing more than 30,000 deaths …

Intestinal SGLT1 as a therapeutic target in COVID‐19‐related diabetes: A “two‐edged sword” hypothesis

T Koufakis, S Metallidis, P Zebekakis… - British Journal of …, 2021 - Wiley Online Library
Emerging data are linking coronavirus disease 2019 (COVID‐19) with an increased risk of
developing new‐onset diabetes. The gut has been so far out of the frame of the discussion …

Anti-inflammatory properties of antidiabetic drugs: a “promised land” in the COVID-19 era?

N Katsiki, E Ferrannini - Journal of Diabetes and its Complications, 2020 - Elsevier
Inflammation is implicated in the development and severity of the coronavirus disease 2019
(COVID-19), as well as in the pathophysiology of diabetes. Diabetes, especially when …

Glucometabolic Perturbations in Type 2 Diabetes Mellitus and Coronavirus Disease 2019: Causes, Consequences, and How to Counter Them Using Novel …

DS Popovic, N Papanas, T Koufakis… - Experimental and …, 2023 - thieme-connect.com
The growing amount of evidence suggests the existence of a bidirectional relation between
coronavirus disease 2019 (COVID-19) and type 2 diabetes mellitus (T2DM), as these two …

Novel molecular evidence related to COVID-19 in patients with diabetes mellitus

YH Liao, JQ Zheng, CM Zheng, KC Lu… - Journal of clinical …, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has rapidly evolved into a global pandemic. The …

Anti-inflammatory effects of GLP-1 in patients with COVID-19

S Sazgarnejad, N Yazdanpanah… - Expert Review of Anti …, 2022 - Taylor & Francis
Introduction Understanding the pathogenesis and risk factors to control the coronavirus
disease 2019 (COVID-19) is necessary. Due to the importance of the inflammatory pathways …

Inflammation: A bridge between diabetes and COVID-19, and possible management with sitagliptin

N Mozafari, S Azadi, S Mehdi-Alamdarlou, H Ashrafi… - Medical hypotheses, 2020 - Elsevier
Patients with SARS-CoV-2 infections experience lymphopenia and inflammatory cytokine
storms in the severe stage of the disease, leading to multi-organ damage. The exact pattern …