Highlights•The antimalarial pipeline has been enriched with new molecules and
targets.•The antimalarial target compound and product profiles have been redefined.•In …

Despite substantial scientific progress over the past two decades, malaria remains a
worldwide burden that causes hundreds of thousands of deaths every year. New, affordable …

Increased efforts in antimalarial drug discovery are urgently needed. The goal must be to
develop safe and affordable new drugs to counter the spread of malaria parasites that are …

Major advances in our understanding of malaria parasite biology have been made. Coupled
with the completion of the malaria genome, this has presented exciting opportunities for …

New antimalarial targets are the prime need for the discovery of potent drug candidates. In
order to fulfill this objective, antimalarial drug researches are focusing on promising targets …

The need for new antimalarials comes from the widespread resistance to those in current
use. New antimalarial targets are required to allow the discovery of chemically diverse …

Recent antimalarial drug discovery has been a race to produce new medicines that
overcome emerging drug resistance, whilst considering safety and improving dosing …

Malaria is a disease that still affects a significant proportion of the global human population.
Whilst advances have been made in lowering the numbers of cases and deaths, it is clear …

In recent years, the research agenda to tackle global morbidity and mortality from malaria
disease has shifted towards innovation, in the hope that efforts at the frontiers of scientific …

Malaria is one of the three most deadly infectious diseases in the world and seriously
endangers human health and life. To reduce the public health burden of this disease …