Machine learning for multi-omics data integration in cancer

Z Cai, RC Poulos, J Liu, Q Zhong - Iscience, 2022 - cell.com
Multi-omics data analysis is an important aspect of cancer molecular biology studies and
has led to ground-breaking discoveries. Many efforts have been made to develop machine …

Integrated multi-omics analyses in oncology: a review of machine learning methods and tools

G Nicora, F Vitali, A Dagliati, N Geifman… - Frontiers in …, 2020 - frontiersin.org
In recent years, high-throughput sequencing technologies provide unprecedented
opportunity to depict cancer samples at multiple molecular levels. The integration and …

Artificial intelligence-based multi-omics analysis fuels cancer precision medicine

X He, X Liu, F Zuo, H Shi, J Jing - Seminars in Cancer Biology, 2023 - Elsevier
With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …

[HTML][HTML] A survey on single and multi omics data mining methods in cancer data classification

Z Momeni, E Hassanzadeh, MS Abadeh… - Journal of Biomedical …, 2020 - Elsevier
Data analytics is routinely used to support biomedical research in all areas, with particular
focus on the most relevant clinical conditions, such as cancer. Bioinformatics approaches, in …

Evaluation and comparison of multi-omics data integration methods for cancer subtyping

R Duan, L Gao, Y Gao, Y Hu, H Xu… - PLoS computational …, 2021 - journals.plos.org
Computational integrative analysis has become a significant approach in the data-driven
exploration of biological problems. Many integration methods for cancer subtyping have …

A comparative study of multi-omics integration tools for cancer driver gene identification and tumour subtyping

A Sathyanarayanan, R Gupta… - Briefings in …, 2020 - academic.oup.com
Oncogenesis and cancer can arise as a consequence of a wide range of genomic
aberrations including mutations, copy number alterations, expression changes and …

Unsupervised multi-omics data integration methods: a comprehensive review

N Vahabi, G Michailidis - Frontiers in genetics, 2022 - frontiersin.org
Through the developments of Omics technologies and dissemination of large-scale
datasets, such as those from The Cancer Genome Atlas, Alzheimer's Disease Neuroimaging …

[HTML][HTML] Multi-omics approaches in cancer research with applications in tumor subtyping, prognosis, and diagnosis

O Menyhárt, B Győrffy - Computational and structural biotechnology journal, 2021 - Elsevier
While cost-effective high-throughput technologies provide an increasing amount of data, the
analyses of single layers of data seldom provide causal relations. Multi-omics data …

[HTML][HTML] Integrative multi-omics approaches in cancer research: from biological networks to clinical subtypes

YJ Heo, C Hwa, GH Lee, JM Park, JY An - Molecules and cells, 2021 - Elsevier
Multi-omics approaches are novel frameworks that integrate multiple omics datasets
generated from the same patients to better understand the molecular and clinical features of …

Machine learning and feature selection for drug response prediction in precision oncology applications

M Ali, T Aittokallio - Biophysical reviews, 2019 - Springer
In-depth modeling of the complex interplay among multiple omics data measured from
cancer cell lines or patient tumors is providing new opportunities toward identification of …