A systematic review of the protective effects of silymarin/silibinin against doxorubicin-induced cardiotoxicity

M Singh, MM Kadhim, A Turki Jalil, SK Oudah… - Cancer Cell …, 2023 - Springer
Purpose Although doxorubicin chemotherapy is commonly applied for treating different
malignant tumors, cardiotoxicity induced by this chemotherapeutic agent restricts its clinical …

The protective effects of silymarin against doxorubicin-induced cardiotoxicity and hepatotoxicity in rats

A Rašković, N Stilinović, J Kolarović, V Vasović… - Molecules, 2011 - mdpi.com
Silymarin is a complex of five major compounds, and silibinin is the most biologically active
component of the complex. The aim of this study was to investigate, evaluate and confirm the …

[PDF][PDF] Doxorubicin-induced cardiotoxicity: molecular mechanism and protection by conventional drugs and natural products

HM Alkuraishy, AI Al-Gareeb… - Int J Clin Oncol Cancer …, 2017 - academia.edu
Doxorubicin is useful anticancer drug because it's used in treatment of acute leukemia,
Hodgkin's and non-Hodgkin's lymphomas, and many other malignant neoplasm. The …

A Systematic Review of the Potential Chemoprotective Effects of Resveratrol on Doxorubicin‐Induced Cardiotoxicity: Focus on the Antioxidant, Antiapoptotic, and Anti …

LF Hu, HR Lan, XM Li, KT Jin - Oxidative medicine and cellular …, 2021 - Wiley Online Library
Purpose. Although doxorubicin chemotherapeutic drug is commonly used to treat various
solid and hematological tumors, its clinical use is restricted because of its adverse effects on …

Efficacy and safety of cardioprotective drugs in chemotherapy-induced cardiotoxicity: an updated systematic review & network meta-analysis

A Mir, Y Badi, S Bugazia, AZ Nourelden, AH Fathallah… - Cardio-Oncology, 2023 - Springer
Background Cancer patients receiving chemotherapy have an increased risk of
cardiovascular complications. This limits the widespread use of lifesaving therapies, often …

Resveratrol, a polyphenol phytoalexin, protects against doxorubicin‐induced cardiotoxicity

J Gu, W Hu, D Zhang - Journal of cellular and molecular …, 2015 - Wiley Online Library
Doxorubicin is the mainstay of treatment for various haematological malignancies and solid
tumours. However, its clinical application may be hampered by dose‐dependent …

The role of melatonin on doxorubicin-induced cardiotoxicity: a systematic review

M Najafi, MRH Shayesteh, K Mortezaee, B Farhood… - Life sciences, 2020 - Elsevier
Purpose Doxorubicin, as an effective chemotherapeutic drug, is commonly used for
combating various solid and hematological tumors. However, doxorubicin-induced …

[HTML][HTML] Cardiotoxicity of anticancer therapeutics

J Dong, H Chen - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
As cancer therapeutics continues to improve and progress, the adverse side effects
associated with anticancer treatments have also attracted more attention and have become …

[HTML][HTML] Cardiotoxicity associated with targeted cancer therapies

ZI Chen, DI Ai - Molecular and clinical oncology, 2016 - … .spandidos-publications.com
Compared with traditional chemotherapy, targeted cancer therapy is a novel strategy in
which key molecules in signaling pathways involved in carcinogenesis and tumor spread …

In vitro and in vivo cardioprotective effects of curcumin against doxorubicin‐induced cardiotoxicity: A systematic review

Q Zhang, L Wu - Journal of oncology, 2022 - Wiley Online Library
Objective. This study aimed to review the potential chemoprotective effects of curcumin
against the doxorubicin‐induced cardiotoxicity. Methods. According to the PRISMA …