Olfactory dysfunction in COVID-19: pathology and long-term implications for brain health

RL Doty - Trends in Molecular Medicine, 2022 - cell.com
Decreased smell function is related to brain health, future mortality, and quality of life. Most
people inflicted with the SARS-CoV-2 virus evidence some measurable smell dysfunction …

Pathogenesis of olfactory disorders in COVID-19

L Ziuzia-Januszewska, M Januszewski - Brain sciences, 2022 - mdpi.com
Since the outbreak of the SARS-CoV-2 pandemic, olfactory disorders have been reported as
a frequent symptom of COVID-19; however, its pathogenesis is still debated. The aim of this …

Olfactory dysfunction in COVID-19: new insights into the underlying mechanisms

R Butowt, K Bilinska, CS von Bartheld - Trends in Neurosciences, 2023 - cell.com
The mechanisms of olfactory dysfunction in COVID-19 are still unclear. In this review, we
examine potential mechanisms that may explain why the sense of smell is lost or altered …

COVID-19 and olfactory dysfunction: a looming wave of dementia?

LM Kay - Journal of neurophysiology, 2022 - journals.physiology.org
Olfactory dysfunction is a hallmark symptom of COVID-19 disease resulting from the SARS-
CoV-2 virus. The cause of the sudden and usually temporary anosmia that most people …

Viral infection and smell loss: The case of COVID‐19

I Glezer, A Bruni‐Cardoso… - Journal of …, 2021 - Wiley Online Library
Olfactory disorders have been increasingly reported in individuals infected with SARS‐CoV‐
2, the virus causing the coronavirus disease 2019 (COVID‐19). Losing the sense of smell …

Loss of olfactory function—early indicator for covid-19, other viral infections and neurodegenerative disorders

H Rebholz, RJ Braun, D Ladage, W Knoll… - Frontiers in …, 2020 - frontiersin.org
The loss of the senses of smell (anosmia) and taste (ageusia) are rather common disorders,
affecting up to 20% of the adult population. Yet, this condition has not received the attention …

Olfactory dysfunction, headache, and mental clouding in adults with long-COVID-19: what is the link between cognition and olfaction? A cross-sectional study

A Di Stadio, MJ Brenner, P De Luca, M Albanese… - Brain Sciences, 2022 - mdpi.com
Smell alteration and cognitive impairment are common features of the Long-COVID
Syndrome. Mental clouding, often described as brain fog, might affect smell by altering …

[HTML][HTML] Revealing the mystery of persistent smell loss in Long COVID patients

JW Park, X Wang, RH Xu - International Journal of Biological …, 2022 - ncbi.nlm.nih.gov
COVID-19 is hopefully approaching its end in many countries as herd immunity develops
and weaker strains of SARS-CoV-2 dominate. However, a new concern occurs over the long …

Mechanisms of SARS-CoV-2-associated anosmia

T Tsukahara, DH Brann, SR Datta - Physiological Reviews, 2023 - journals.physiology.org
Anosmia, the loss of the sense of smell, is one of the main neurological manifestations of
COVID-19. Although the SARS-CoV-2 virus targets the nasal olfactory epithelium, current …

COVID-19–related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters

GD De Melo, F Lazarini, S Levallois… - Science translational …, 2021 - science.org
Whereas recent investigations have revealed viral, inflammatory, and vascular factors
involved in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung …