Sex hormone binding globulin and insulin resistance

IR Wallace, MC McKinley, PM Bell… - Clinical …, 2013 - Wiley Online Library
Sex hormone binding globulin (SHBG) is a glycoprotein composed of two 373‐amino‐acid
subunits. The SHBG gene and a promotor region have been identified. The SHBG receptor …

Sex hormone-binding globulin and type 2 diabetes mellitus

TN Le, JE Nestler, JF Strauss, EP Wickham - Trends in Endocrinology & …, 2012 - cell.com
Sex hormone-binding globulin (SHBG) has emerged as one of the multiple genetic and
environmental factors that potentially contribute to the pathophysiology of type 2 diabetes …

Level of sex hormone-binding globulin is positively correlated with insulin sensitivity in men with type 2 diabetes

KI Birkeland, KF Hanssen, PA Torjesen… - The journal of clinical …, 1993 - academic.oup.com
The level of sex hormone-binding globulin (SHBG) is associated with glucose metabolism in
nondiabetic women and men, and the finding of low SHBG levels is suggested to be a …

Sex hormone-binding globulin gene expression and insulin resistance

SJ Winters, J Gogineni, M Karegar… - The Journal of …, 2014 - academic.oup.com
Context: The plasma level of sex hormone binding globulin (SHBG), a glycoprotein
produced by hepatocytes, is subject to genetic, hormonal, metabolic, and nutritional …

Sex hormone—binding globulin and insulin resistance in African-American women

K Sherif, H Kushner, BE Falkner - Metabolism, 1998 - Elsevier
Sex hormone—binding globulin (SHBG) binds testosterone, determining the level of free,
biologically active hormone, and is a sensitive indicator of androgen status in women. SHBG …

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

JRB Perry, MN Weedon, C Langenberg… - Human molecular …, 2010 - academic.oup.com
Epidemiological studies consistently show that circulating sex hormone binding globulin
(SHBG) levels are lower in type 2 diabetes patients than non-diabetic individuals, but the …

Sex hormone–binding globulin and risk of type 2 diabetes in women and men

EL Ding, Y Song, JAE Manson, DJ Hunter… - … England Journal of …, 2009 - Mass Medical Soc
Background Circulating sex hormone–binding globulin levels are inversely associated with
insulin resistance, but whether these levels can predict the risk of developing type 2 …

Pathophysiology of sex hormone binding globulin (SHBG): relation to insulin

M Pugeat, JC Crave, M Elmidani, MH Nicolas… - The Journal of steroid …, 1991 - Elsevier
In humans, the plasma level of sex hormone binding globulin (SHBG) is regulated by
several hormones. We have now accumulated evidence that SHBG is also intimately related …

Decreased sex hormone-binding globulin predicts noninsulin-dependent diabetes mellitus in women but not in men

SM Haffner, RA Valdez, PA Morales… - The Journal of …, 1993 - academic.oup.com
Sex hormones may influence risk factors for noninsulin-dependent diabetes mellitus
(NIDDM). Decreased sex hormone-binding globulin (SHBG; an indirect measure of …

Sex hormone-binding globulin and glucose tolerance in postmenopausal women: The Rancho Bernardo Study

D Goodman-Gruen, E Barrett-Connor - Diabetes Care, 1997 - Am Diabetes Assoc
OBJECTIVE Sex hormone-binding globulin (SHBG) has been shown to be associated with
several diabetes risk factors, including total body fat, central obesity, and hyperinsulinemic …