Substance use disorders (SUDs) are prevalent and result in an array of negative
consequences. They are influenced by genetic factors (h2=~ 50%). Recent years have …

Substance use disorder (SUD) often co‐occur at high prevalence with other psychiatric
conditions. Among them, attention‐deficit and hyperactivity disorder (ADHD) is present in …

Genome-wide association studies (GWAS) currently represent the most systematic approach
to genetic research into complex disorders. They can detect associations of common …

Background Substance use disorders (SUD) are a category of psychiatric disorders with a
large epidemiological and societal impact around the world. In the last decades, a large …

Using large twin, family, and adoption studies conducted at the Minnesota Center for Twin
and Family Research, we describe our efforts to develop measures of substance use …

Substance use disorders (SUDs) are conditions in which the use of legal or illegal
substances, such as nicotine, alcohol or opioids, results in clinical and functional …

Drug‐related phenotypes are common complex and highly heritable traits. In the last few
years, candidate gene (CGAS) and genome‐wide association studies (GWAS) have …

Background Substance use disorder (SUD) remains a significant public health issue. A
greater understanding of how genes and environment interact to regulate phenotypes …

Genome‐wide association studies (GWAS) of alcohol dependence (AD) have reliably
identified variation within alcohol metabolizing genes (eg, ADH1B) but have inconsistently …

Alcohol use disorder (AUD) represents a significant and ongoing public health concern with
12-month prevalence estimates of∼ 5.6%. Quantitative genetic studies suggest a heritability …