International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos - Pharmacological reviews, 2017 - ASPET
Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

JL Wallace, R Wang - Nature reviews Drug discovery, 2015 - nature.com
Hydrogen sulfide (H2S) has become recognized as an important signalling molecule
throughout the body, contributing to many physiological and pathological processes. In …

Synthesis and Biological Effects of Hydrogen Sulfide (H2S): Development of H2S-Releasing Drugs as Pharmaceuticals

G Caliendo, G Cirino, V Santagada… - Journal of medicinal …, 2010 - ACS Publications
Gaseous transmitters are a growing family of regulatory molecules involved in multilevel
regulation of physiological and pathological functions in mammalian tissues. 1 Hydrogen …

A practical look at the chemistry and biology of hydrogen sulfide

KR Olson - Antioxidants & redox signaling, 2012 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) is garnering increasing interest as a
biologically relevant signaling molecule. The effects of H2S have now been observed in …

Progress and perspective on hydrogen sulfide donors and their biomedical applications

ZL Song, L Zhao, T Ma, A Osama… - Medicinal Research …, 2022 - Wiley Online Library
Following the discovery of nitric oxide (NO) and carbon monoxide (CO), hydrogen sulfide
(H2S) has been identified as the third gasotransmitter in humans. Increasing evidence have …

A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications

CR Powell, KM Dillon, JB Matson - Biochemical pharmacology, 2018 - Elsevier
Hydrogen sulfide (H 2 S) is a ubiquitous small gaseous signaling molecule, playing an
important role in many physiological processes and joining nitric oxide and carbon …

Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools

M Whiteman, S Le Trionnaire, M Chopra, B Fox… - Clinical …, 2011 - portlandpress.com
H2S (hydrogen sulfide) is a well known and pungent gas recently discovered to be
synthesized enzymatically in mammalian and human tissues. In a relatively short period of …

The therapeutic potential of hydrogen sulfide: separating hype from hope

KR Olson - American Journal of Physiology-Regulatory …, 2011 - journals.physiology.org
Hydrogen sulfide (H2S) has become the hot new signaling molecule that seemingly affects
all organ systems and biological processes in which it has been investigated. It has also …

Pharmacological tools for hydrogen sulphide research: a brief, introductory guide for beginners

A Papapetropoulos, M Whiteman… - British journal of …, 2015 - Wiley Online Library
The purpose of this brief review is to help researchers in their initial approach to the H2S
field and to provide answers for the most frequently posed questions by newcomers to the …

Hydrogen sulfide in pharmacology and medicine–an update

J Bełtowski - Pharmacological Reports, 2015 - Elsevier
Hydrogen sulfide (H 2 S) is the endogenously produced gasotransmitter involved in the
regulation of nervous system, cardiovascular functions, inflammatory response …