Potential impact of PI3K-AKT signaling pathway genes, KLF-14, MDM4, miRNAs 27a, miRNA-196a genetic alterations in the predisposition and progression of breast …
Simple Summary The genomic landscape of breast cancer (BC) is complex. Previous
research studies have not extensively elucidated the correlation of genotypes and allele …
research studies have not extensively elucidated the correlation of genotypes and allele …
Genome-wide pathway analysis of breast cancer
YH Lee, JH Kim, GG Song - Tumor Biology, 2014 - Springer
The aim of this study was to identify candidate single-nucleotide polymorphisms (SNPs) that
might affect susceptibility to breast cancer and then elucidate their potential mechanisms …
might affect susceptibility to breast cancer and then elucidate their potential mechanisms …
Association between mitogen-activated protein kinase kinase kinase 1 polymorphisms and breast cancer susceptibility: a meta-analysis of 20 case-control studies
Q Zheng, J Ye, H Wu, Q Yu, J Cao - PLoS One, 2014 - journals.plos.org
Background The genome-wide single-nucleotide polymorphisms (SNPs) profiles can be
used as diagnostic markers for human cancers. The associations between mitogen …
used as diagnostic markers for human cancers. The associations between mitogen …
In‐silico and in‐vitro evidence suggest LINC01405 as a sponge for miR‐29b and miR‐497‐5p, and a potential regulator of Wnt, PI3K, and TGFB signaling pathways in …
R Norouzi, Z Mohamadzade, R Norouzi… - Cancer …, 2024 - Wiley Online Library
Background Carcinoma of the breast, a prevailing factor in female mortality worldwide,
involves dysregulation of lncRNAs and microRNAs. Aim The main goal of this research was …
involves dysregulation of lncRNAs and microRNAs. Aim The main goal of this research was …
PIK3R1 underexpression is an independent prognostic marker in breast cancer
M Cizkova, S Vacher, D Meseure, M Trassard, A Susini… - BMC cancer, 2013 - Springer
Background The present study focused on the prognostic roles of PIK3CA and PIK3R1
genes and additional PI3K pathway-associated genes in breast cancer. Methods The …
genes and additional PI3K pathway-associated genes in breast cancer. Methods The …
Mutation of genes of the PI3K/AKT pathway in breast cancer supports their potential importance as biomarker for breast cancer aggressiveness
Deregulation of phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway is closely
associated with cancer development and cancer progression. PIK3CA, AKT1, and PTEN are …
associated with cancer development and cancer progression. PIK3CA, AKT1, and PTEN are …
Integrated analysis of differentially expressed genes in breast cancer pathogenesis
D Chen, H Yang - Oncology letters, 2015 - spandidos-publications.com
The present study aimed to detect the differences between breast cancer cells and normal
breast cells, and investigate the potential pathogenetic mechanisms of breast cancer. The …
breast cells, and investigate the potential pathogenetic mechanisms of breast cancer. The …
A single nucleotide polymorphism in PIK3CA gene is inversely associated with P53 protein expression in breast cancer
B Pang, SP Sun, L Gao, RL Zhu, L Zhang, C An… - Medical Oncology, 2014 - Springer
Single nucleotide polymorphism (SNP) rs17849071 was recently reported to be inversely
associated with PIK3CA amplification in follicular thyroid cancer, but the main function of this …
associated with PIK3CA amplification in follicular thyroid cancer, but the main function of this …
Identification of New Key genes and their association with breast Cancer occurrence and poor survival using in Silico and in Vitro methods
Breast cancer is one of the most prevalent types of cancer diagnosed globally and continues
to have a significant impact on the global number of cancer deaths. Despite all efforts of …
to have a significant impact on the global number of cancer deaths. Despite all efforts of …
Family specific genetic predisposition to breast cancer: results from Tunisian whole exome sequenced breast cancer cases
Y Hamdi, M Boujemaa, M Ben Rekaya… - Journal of translational …, 2018 - Springer
Background A family history of breast cancer has long been thought to indicate the presence
of inherited genetic events that predispose to this disease. In North Africa, many specific …
of inherited genetic events that predispose to this disease. In North Africa, many specific …