Dynamic regulation and key roles of ribonucleic acid methylation

J Zou, H Liu, W Tan, Y Chen, J Dong, S Bai… - Frontiers in Cellular …, 2022 - frontiersin.org
Ribonucleic acid (RNA) methylation is the most abundant modification in biological systems,
accounting for 60% of all RNA modifications, and affects multiple aspects of RNA (including …

Dynamic RNA methylation modifications and their regulatory role in mammalian development and diseases

W Yang, Y Zhao, Y Yang - Science China Life Sciences, 2024 - Springer
Among over 170 different types of chemical modifications on RNA nucleobases identified so
far, RNA methylation is the major type of epitranscriptomic modifications existing on almost …

An Overview of Current Detection Methods for RNA Methylation

B Sağlam, B Akgül - International Journal of Molecular Sciences, 2024 - mdpi.com
Epitranscriptomic mechanisms, which constitute an important layer in post-transcriptional
gene regulation, are involved in numerous cellular processes under health and disease …

Emerging roles of RNA methylation in development

MK Wang, CC Gao, YG Yang - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus More than 170 different types of chemical modifications have been identified on
diverse types of RNA, collectively known as the epitranscriptome. Among them, N 6 …

New Insights on the Role of N6-Methyladenosine RNA Methylation in the Physiology and Pathology of the Nervous System

G Dermentzaki, F Lotti - Frontiers in Molecular Biosciences, 2020 - frontiersin.org
RNA modifications termed epitranscriptomics represent an additional layer of gene
regulation similar to epigenetic mechanisms operating on DNA. The dynamic nature and the …

[HTML][HTML] Role of RNA methyltransferases in tissue renewal and pathology

S Blanco, M Frye - Current opinion in cell biology, 2014 - Elsevier
Over the last five decades more than 100 types of RNA modifications have been identified in
organism of all kingdoms of life, yet their function and biological relevance remain largely …

[HTML][HTML] Principles of RNA methylation and their implications for biology and medicine

Y Zhou, Y Kong, W Fan, T Tao, Q Xiao, N Li… - Biomedicine & …, 2020 - Elsevier
RNA methylation is a post-transcriptional level of regulation. At present, more than 150 kinds
of RNA modifications have been identified. They are widely distributed in messenger RNA …

Epitranscriptomics: regulation of mRNA metabolism through modifications

E Peer, G Rechavi, D Dominissini - Current opinion in chemical biology, 2017 - Elsevier
Highlights•Over 100 types of chemical modifications exist in cellular RNAs.•Technological
and conceptual breakthroughs identified internal modifications in mRNA.•Newly discovered …

[HTML][HTML] The epitranscriptome in stem cell biology and neural development

C Vissers, A Sinha, G Ming, H Song - Neurobiology of disease, 2020 - Elsevier
The blossoming field of epitranscriptomics has recently garnered attention across many
fields by findings that chemical modifications on RNA have immense biological …

N 6-methyladenosine RNA methylation: From regulatory mechanisms to potential clinical applications

P Li, Y Wang, Y Sun, S Jiang, J Li - Frontiers in Cell and …, 2022 - frontiersin.org
Epitranscriptomics has emerged as another level of epigenetic regulation similar to DNA
and histone modifications. N 6-methyladenosine (m6A) is one of the most prevalent and …