[HTML][HTML] Volume of the posterior hippocampus mediates age-related differences in spatial context memory and is correlated with increased activity in lateral frontal …

J Snytte, C Fenerci, S Rajagopal, C Beaudoin… - NeuroImage, 2022 - Elsevier
Healthy aging is associated with episodic memory decline, particularly in the ability to
encode and retrieve object-context associations (context memory). Neuropsychological and …

Human aging alters the neural computation and representation of space

NW Schuck, CF Doeller, TA Polk, U Lindenberger… - NeuroImage, 2015 - Elsevier
The hippocampus and striatum are core neural circuits involved in spatial learning and
memory. Although both neural systems support spatial navigation, experimental and …

The role of hippocampal subfield volume and fornix microstructure in episodic memory across the lifespan

CM Foster, KM Kennedy, DA Hoagey… - …, 2019 - Wiley Online Library
Advancing age is associated with both declines in episodic memory and degradation of
medial temporal lobe (MTL) structure. The contribution of MTL to episodic memory is …

Episodic memory in normal aging and Alzheimer disease: Insights from imaging and behavioral studies

D Tromp, A Dufour, S Lithfous, T Pebayle… - Ageing research …, 2015 - Elsevier
Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …

Age-related changes in the three-way correlation between anterior hippocampus volume, whole-brain patterns of encoding activity and subsequent context retrieval

D Maillet, MN Rajah - Brain research, 2011 - Elsevier
Age-related declines in memory for context have been linked to volume loss in the
hippocampal head (HH) with age. However, it remains unclear how this volumetric decline …

Longitudinal structure–function correlates in elderly reveal MTL dysfunction with cognitive decline

J Persson, S Pudas, J Lind, K Kauppi… - Cerebral …, 2012 - academic.oup.com
By integrating behavioral measures and imaging data, previous investigations have
explored the relationship between biological markers of aging and cognitive functions …

Contributions of hippocampal subfields and subregions to episodic memory performance in healthy cognitive aging

N Malykhin, W Pietrasik, KN Hoang, Y Huang - Neurobiology of Aging, 2024 - Elsevier
In the present study we investigated whether hippocampal subfield (cornu ammonis 1–3,
dentate gyrus, and subiculum) and anteroposterior hippocampal subregion (head, body …

Brain events underlying episodic memory changes in aging: a longitudinal investigation of structural and functional connectivity

AM Fjell, MH Sneve, AB Storsve, H Grydeland… - Cerebral …, 2016 - academic.oup.com
Episodic memories are established and maintained by close interplay between
hippocampus and other cortical regions, but degradation of a fronto-striatal network has …

[HTML][HTML] Model of brain maintenance reveals specific change-change association between medial-temporal lobe integrity and episodic memory

J Johansson, A Wåhlin, A Lundquist, AM Brandmaier… - Aging Brain, 2022 - Elsevier
Brain maintenance has been identified as a major determinant of successful memory aging.
However, the extent to which brain maintenance in support of successful memory aging is …

[HTML][HTML] Differential medial temporal lobe morphometric predictors of item-and relational-encoded memories in healthy individuals and in individuals with mild …

JJ Gomar, JD Ragland, AM Uluğ, A Sousa… - Alzheimer's & Dementia …, 2017 - Elsevier
Introduction Episodic memory processes are supported by different subregions of the medial
temporal lobe (MTL). In contrast to a unitary model of memory recognition supported solely …