Extracellular vesicles in cancer immune microenvironment and cancer immunotherapy

F Xie, X Zhou, M Fang, H Li, P Su, Y Tu… - Advanced …, 2019 - Wiley Online Library
Extracellular vesicles (EVs) are secreted by almost all cells. They contain proteins, lipids,
and nucleic acids which are delivered from the parent cells to the recipient cells. Thereby …

[HTML][HTML] Recent advances on the role of tumor exosomes in immunosuppression and disease progression

P Filipazzi, M Bürdek, A Villa, L Rivoltini… - Seminars in cancer …, 2012 - Elsevier
Exosomes are endosomal-derived nanovesicles released by most cells types, including
tumor cells, and principally involved in intercellular communication in physiology and …

Exosome-based immunotherapy: a promising approach for cancer treatment

Z Xu, S Zeng, Z Gong, Y Yan - Molecular cancer, 2020 - Springer
In the era of the rapid development of cancer immunotherapy, there is a high level of interest
in the application of cell-released small vesicles that stimulate the immune system. As cell …

[HTML][HTML] The functions and clinical applications of tumor-derived exosomes

Y Shao, Y Shen, T Chen, F Xu, X Chen, S Zheng - Oncotarget, 2016 - ncbi.nlm.nih.gov
Exosomes are extracellular vesicles with diameters ranging from 30 to 150 nm. They can be
secreted by all cell types and transfer information in the form of their contents, which include …

Exosomes, their biogenesis and role in inter-cellular communication, tumor microenvironment and cancer immunotherapy

KK Jella, TH Nasti, Z Li, SR Malla, ZS Buchwald… - Vaccines, 2018 - mdpi.com
Exosomes are extracellular vesicles ranging from 30 to 150 nm in diameter that contain
molecular constituents of their host cells. They are released from different types of cells …

The roles of tumor‐derived exosomes in cancer pathogenesis

C Yang, PD Robbins - Journal of Immunology Research, 2011 - Wiley Online Library
Exosomes are endosome‐derived, 30–100 nm small membrane vesicles released by most
cell types including tumor cells. They are enriched in a selective repertoire of proteins and …

[HTML][HTML] Exosomes and their role in the micro-/macro-environment: a comprehensive review

N Javeed, D Mukhopadhyay - Journal of biomedical research, 2017 - ncbi.nlm.nih.gov
The importance of extracellular vesicles (EVs) in cell-cell communication has long been
recognized due to their ability to transfer important cellular cargoes such as DNA, mRNA …

Emerging prospects of exosomes for cancer treatment: from conventional therapy to immunotherapy

GH Nam, Y Choi, GB Kim, S Kim, SA Kim… - Advanced …, 2020 - Wiley Online Library
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …

Exosomes and their role in cancer progression

Y Liu, K Shi, Y Chen, X Wu, Z Chen, K Cao… - Frontiers in …, 2021 - frontiersin.org
Exosomes from extracellular vesicles can activate or inhibit various signaling pathways by
transporting proteins, lipids, nucleic acids and other substances to recipient cells. In …

Roles of exosomes in immunotherapy for solid cancers

C Lyu, H Sun, Z Sun, Y Liu, Q Wang - Cell Death & Disease, 2024 - nature.com
Although immunotherapy has made breakthrough progress, its efficacy in solid tumours
remains unsatisfactory. Exosomes are the main type of extracellular vesicles that can deliver …